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Drug ReportsMaxacalcitol
Maxacalcitol
Maxacalcitol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target vitamin D3 receptor.
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Clinical
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Variants
Financial
Trends
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
2207 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Macular degenerationD008268EFO_0001365H35.30—354112
Wet macular degenerationD057135EFO_0004683———12—3
Multiple sclerosisD009103EFO_0003885G35———123
Relapsing-remitting multiple sclerosisD020529EFO_0003929————123
SclerosisD012598—————123
PsoriasisD011565EFO_0000676L40———112
Polypoidal choroidal vasculopathyD000092342—————1—1
Vascular diseasesD014652EFO_0004264I77———1—1
Immunosuppression therapyD007165—————1—1
Myocardial infarctionD009203EFO_0000612I21———1—1
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Choroidal neovascularizationD020256———13—25
Macular edemaD008269————2—24
Retinal diseasesD012164—H35.9——1——1
Eye diseasesD005128EFO_0003966H44——1——1
Retinal neovascularizationD015861—H35.05——1——1
Degenerative myopiaD047728—H44.2——1——1
Retinal vein occlusionD012170EFO_1001157H34.81——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Retinal detachmentD012163EFO_0005773H33.2—1———1
UveitisD014605EFO_1001231H20.9—1———1
Ornithine carbamoyltransferase deficiency diseaseD020163EFO_0007409E72.4—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Pathologic neovascularizationD009389——————22
MyopiaD009216EFO_0003927H52.1————11
Vision disordersD014786—H53.11————11
Low visionD015354——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMaxacalcitol
INNmaxacalcitol
Description
Maxacalcitol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target vitamin D3 receptor.
Classification
Small molecule
Drug classvitamin D analogs
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C=C1/C(=C\C=C2/CCC[C@]3(C)[C@@H]([C@H](C)OCCC(C)(C)O)CC[C@@H]23)C[C@@H](O)C[C@@H]1O
Identifiers
PDB—
CAS-ID103909-75-7
RxCUI—
ChEMBL IDCHEMBL333950
ChEBI ID—
PubChem CID12019456
DrugBankDB06272
UNII IDN2UJM5NBF6 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
VDR
VDR
Organism
Homo sapiens
Gene name
VDR
Gene synonyms
NR1I1
NCBI Gene ID
Protein name
vitamin D3 receptor
Protein synonyms
1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, protein phosphatase 1, regulatory subunit 163, vitamin D (1,25- dihydroxyvitamin D3) receptor
Uniprot ID
Mouse ortholog
Vdr (22337)
vitamin D3 receptor (Q922X0)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 165,926 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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181,076 adverse events reported
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