Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Fragile x syndrome | D005600 | — | Q99.2 | 1 | 6 | 1 | — | — | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 8 | — | — | — | 8 |
Dyskinesias | D020820 | HP_0002310 | G24 | — | 5 | — | — | — | 5 |
Parkinsonian disorders | D020734 | HP_0001300 | G20.C | — | 3 | — | — | — | 3 |
Movement disorders | D009069 | HP_0100022 | — | — | 3 | — | — | — | 3 |
Cocaine-related disorders | D019970 | — | F14 | 1 | 1 | — | — | — | 2 |
Drug-induced dyskinesia | D004409 | EFO_1000904 | — | — | 1 | — | — | — | 1 |
Huntington disease | D006816 | Orphanet_399 | G10 | — | 1 | — | — | — | 1 |
Chorea | D002819 | EFO_0004152 | G25.5 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Alcoholism | D000437 | EFO_0003829 | F10.1 | 2 | — | — | — | — | 2 |
Hepatic insufficiency | D048550 | — | — | 1 | — | — | — | — | 1 |
Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 1 | — | — | — | — | 1 |
Alcohol drinking | D000428 | EFO_0004329 | — | 1 | — | — | — | — | 1 |
Drug common name | Mavoglurant |
INN | mavoglurant |
Description | Mavoglurant (developmental code name AFQ-056) is an experimental drug candidate for the treatment of fragile X syndrome and other conditions. It exerts its effect as an antagonist of the metabotropic glutamate receptor 5 (mGluR5).
|
Classification | Small molecule |
Drug class | metabotropic glutamate receptor antagonists, negative allosteric modulators |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | COC(=O)N1CC[C@@H]2[C@H]1CCC[C@@]2(O)C#Cc1cccc(C)c1 |
PDB | — |
CAS-ID | 1636881-61-2 |
RxCUI | — |
ChEMBL ID | CHEMBL3087515 |
ChEBI ID | — |
PubChem CID | 9926832 |
DrugBank | — |
UNII ID | GT0I9SV4F6 (ChemIDplus, GSRS) |