Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CAMZYOS | Bristol Myers Squibb | N-214998 RX | 2022-04-28 | 4 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
camzyos | New Drug Application | 2024-04-30 |
Expiration | Code | ||
---|---|---|---|
MAVACAMTEN, CAMZYOS, BRISTOL | |||
2029-04-28 | ODE-398 | ||
2027-04-28 | NCE | ||
2026-06-15 | M-297 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertrophic cardiomyopathy | D002312 | EFO_0000538 | I42.1 | 2 | 4 | 7 | 1 | 8 | 21 |
Cardiomyopathies | D009202 | EFO_0000318 | I42 | 2 | 4 | 7 | 1 | 8 | 21 |
Hypertrophy | D006984 | EFO_0002460 | — | 1 | 4 | 7 | 1 | 5 | 17 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Heart failure | D006333 | HP_0001635 | I50 | — | 1 | — | — | — | 1 |
Ventricular outflow obstruction | D014694 | EFO_1001448 | — | — | 1 | — | — | — | 1 |
Left ventricular outflow obstruction | D000092242 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 7 | — | — | — | — | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pregnancy rate | D018873 | — | — | — | — | — | — | 1 | 1 |
Breast feeding | D001942 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Mavacamten |
INN | mavacamten |
Description | Mavacamten, sold under the brand name Camzyos, is a medication used to treat obstructive hypertrophic cardiomyopathy.
|
Classification | Small molecule |
Drug class | allosteric cardiac myosin modulators |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O |
PDB | — |
CAS-ID | 1642288-47-8 |
RxCUI | — |
ChEMBL ID | CHEMBL4297517 |
ChEBI ID | — |
PubChem CID | 117761397 |
DrugBank | DB14921 |
UNII ID | QX45B99R3J (ChemIDplus, GSRS) |