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Drug ReportsMarstacimab
Marstacimab
Hympavzi (marstacimab) is an antibody pharmaceutical. Marstacimab was first approved as Hympavzi on 2024-10-11. It is used to treat hemophilia a and hemophilia b in the USA. It is known to target tissue factor pathway inhibitor.
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Drug
Target
Variants
Financial
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Events Timeline
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Hympavzi
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Marstacimab
Tradename
Proper name
Company
Number
Date
Products
Hympavzimarstacimab-hncqPfizerN-761369 RX2024-10-11
2 products
Labels
FDA
EMA
Brand Name
Status
Last Update
hympavziBiologic Licensing Application2025-02-12
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hemophilia aD006467EFO_0007267D662237
Hemophilia bD002836D6733
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMarstacimab
INNmarstacimab
Description
Marstacimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
Classification
Antibody
Drug classmonoclonal antibodies
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Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID
RxCUI
ChEMBL IDCHEMBL3990039
ChEBI ID
PubChem CID
DrugBank
UNII ID0UB3OA67O7 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
TFPI
TFPI
Organism
Homo sapiens
Gene name
TFPI
Gene synonyms
LACI, TFPI1
NCBI Gene ID
Protein name
tissue factor pathway inhibitor
Protein synonyms
anti-convertin, EPI, Extrinsic pathway inhibitor, LACI, Lipoprotein-associated coagulation inhibitor, tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Uniprot ID
Mouse ortholog
Tfpi (21788)
tissue factor pathway inhibitor (Q9Z2U8)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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