MOCETINOSTAT
Mocetinostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target histone deacetylase 3, histone deacetylase 1, and histone deacetylase 2.
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Commercial
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Clinical
Clinical Trials
23 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | — | C34.90 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | MOCETINOSTAT |
| INN | mocetinostat |
| Description | Mocetinostat (MGCD0103) is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers including follicular lymphoma, Hodgkin's lymphoma and acute myelogenous leukemia.
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| Classification | Small molecule |
| Drug class | enzyme inhibitors: histone deacetylase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 726169-73-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL272980 |
| ChEBI ID | — |
| PubChem CID | 9865515 |
| DrugBank | DB11830 |
| UNII ID | A6GWB8T96J (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
HDAC1
HDAC1
Variants
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Trends
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Safety
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Adverse Events
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17 adverse events reported
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