Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | — | 2 | — | — | — | 2 |
Fatty liver | D005234 | EFO_0003934 | — | — | 2 | — | — | — | 2 |
Hypercholesterolemia | D006937 | HP_0003124 | — | — | 2 | — | — | — | 2 |
Liver diseases | D008107 | HP_0002910 | K70-K77 | — | 1 | — | — | — | 1 |
Hyperlipidemias | D006949 | HP_0003077 | E78.5 | — | 1 | — | — | — | 1 |
Drug common name | MB07811 |
INN | — |
Description | VK2809 (formerly known as MB07811) is a thyromimetic prodrug whose active form is selective for the THR-β isoform. It is being developed by Viking Therapeutics in a phase II trial for the treatment of nonalcoholic steatohepatitis and is also being investigated for glycogen storage disease type Ia.
|
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Cc1cc(OC[P@@]2(=O)OCC[C@@H](c3cccc(Cl)c3)O2)cc(C)c1Cc1ccc(O)c(C(C)C)c1 |
PDB | — |
CAS-ID | 852948-13-1 |
RxCUI | — |
ChEMBL ID | CHEMBL457748 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB15137 |
UNII ID | — |