MAVATREP
Mavatrep is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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FDA approval date
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Patent expiration date
Study first post date
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Commercial
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 2 | — | — | — | — | 2 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 2 | — | — | — | — | 2 |
| Pain | D010146 | EFO_0003843 | R52 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | MAVATREP |
| INN | mavatrep |
| Description | Mavatrep (JNJ‐39439335) is a TRPV1 receptor selective competitive antagonist. It is an investigational analgesic that may be a potential treatment for pain and/or inflammation.
|
| Classification | Small molecule |
| Drug class | transient receptor potential antagonists; vanilloid 1 receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(C(F)(F)F)cc3)nc2c1 |
Identifiers
| PDB | — |
| CAS-ID | 956274-94-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2364618 |
| ChEBI ID | — |
| PubChem CID | 17751090 |
| DrugBank | DB12875 |
| UNII ID | F197218T99 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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