Lysergide
Lysergide is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target 5-hydroxytryptamine receptor 7, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 1F, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, and 5-hydroxytryptamine receptor 1A.
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Clinical
Clinical Trials
63 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Mucopolysaccharidosis iv | D009085 | — | E76.210 | 2 | 5 | 2 | — | 2 | 9 |
| Mucopolysaccharidoses | D009083 | — | E76.3 | 2 | 5 | 2 | — | 2 | 9 |
| Syndrome | D013577 | — | — | 1 | 4 | 1 | — | 1 | 6 |
| Osteochondrodysplasias | D010009 | Orphanet_800 | G71.13 | — | — | 1 | — | 1 | 2 |
Indications Phases 2
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Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Lysergide |
| INN | lysergide |
| Description | Lysergic acid diethylamide is an ergoline alkaloid arising from formal condensation of lysergic acid with diethylamine. It has a role as a hallucinogen, a serotonergic agonist and a dopamine agonist. It is an ergoline alkaloid, an organic heterotetracyclic compound and a monocarboxylic acid amide. It is functionally related to a lysergamide. |
| Classification | Small molecule |
| Drug class | ergot alkaloid deriviatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCN(CC)C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 |
Identifiers
| PDB | — |
| CAS-ID | 50-37-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL263881 |
| ChEBI ID | 6605 |
| PubChem CID | 5761 |
| DrugBank | DB04829 |
| UNII ID | 8NA5SWF92O (ChemIDplus, GSRS) |
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Safety
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306 adverse events reported
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