Lobeline - PharmaKB

Lobeline

Lobeline is a small molecule pharmaceutical. It is currently being investigated in clinical studies.

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Clinical Trials

96 clinical trials

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Indications Phases 4

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Tobacco use cessation	D020340	—	—	—	—	—	1	—	1

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Indications Phases 1

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Indications Without Phase

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Epidemiology

Epidemiological information for investigational and approved indications

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Drug

General

Drug common name	Lobeline
INN	lobeline
Description	(-)-lobeline is an optically active piperidine alkaloid having a 2-oxo-2-phenylethyl substituent at the 2-position and a 2-hydroxy-2-phenylethyl group at the 6-position. It has a role as a nicotinic acetylcholine receptor agonist. It is a piperidine alkaloid, a tertiary amine and an aromatic ketone.
Classification	Small molecule
Drug class	—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)	CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1