Lipopolysaccharide
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135 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 17 | — | — | 2 | 6 | 25 |
| Inflammation | D007249 | MP_0001845 | — | 8 | 1 | — | 1 | 13 | 22 |
| Sepsis | D018805 | HP_0100806 | A41.9 | 1 | 3 | 2 | 1 | 12 | 17 |
| Endotoxemia | D019446 | — | — | 4 | 1 | — | 4 | 5 | 13 |
| Asthma | D001249 | EFO_0000270 | J45 | 3 | — | — | 1 | 3 | 7 |
| Insulin resistance | D007333 | HP_0000855 | — | — | 1 | — | 1 | 1 | 3 |
| Infections | D007239 | EFO_0000544 | — | 1 | — | — | 1 | — | 2 |
| Cholera | D002771 | — | A00 | — | — | — | 1 | 1 | 2 |
| Hereditary angioedemas | D054179 | EFO_0004131 | — | — | — | — | 1 | — | 1 |
| Liver diseases | D008107 | HP_0002910 | K70-K77 | — | — | — | 1 | — | 1 |
Show 9 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pneumonia | D011014 | EFO_0003106 | — | 3 | 1 | 1 | — | 3 | 7 |
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | 1 | 1 | — | — | 1 |
| Bacterial infections | D001424 | — | A49 | — | — | 1 | — | — | 1 |
| Gram-negative bacterial infections | D016905 | — | — | — | — | 1 | — | — | 1 |
| Myofascial pain syndromes | D009209 | EFO_1001054 | — | — | 1 | 1 | — | — | 1 |
| Fibromyalgia | D005356 | EFO_0005687 | M79.1 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Toxemia | D014115 | — | — | 1 | 2 | — | — | 7 | 9 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | — | — | 3 | 4 |
| Depression | D003863 | — | F33.9 | 3 | 2 | — | — | — | 4 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | 3 | 2 | — | — | — | 4 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | 1 | 2 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | 1 | — | — | 1 | 2 |
| Multiple organ failure | D009102 | EFO_1001373 | — | — | 1 | — | — | 1 | 2 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 1 | 2 | — | — | — | 2 |
| Alcohol drinking | D000428 | EFO_0004329 | — | — | 1 | — | — | 1 | 2 |
| Leukemia | D007938 | — | C95 | 1 | 1 | — | — | — | 1 |
Show 18 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 3 | — | — | — | — | 3 |
| Neoplasms | D009369 | — | C80 | 2 | — | — | — | — | 2 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | — | — | — | 1 | 2 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | 2 | — | — | — | — | 2 |
| Hiv | D006678 | — | — | 1 | — | — | — | 1 | 2 |
| Immunity | D007109 | — | — | 2 | — | — | — | — | 2 |
| Hookworm infections | D006725 | EFO_0007314 | B76 | 1 | — | — | — | — | 1 |
| Ancylostomiasis | D000724 | EFO_0007145 | B76.0 | 1 | — | — | — | — | 1 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | — | — | — | — | 1 |
| Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | 1 | — | — | — | — | 1 |
Show 6 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Septic shock | D012772 | — | A48.3 | — | — | — | — | 5 | 5 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | — | 4 | 4 |
| Illness behavior | D055809 | — | — | — | — | — | — | 3 | 3 |
| Shock | D012769 | — | R57.1 | — | — | — | — | 3 | 3 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | — | — | — | 3 | 3 |
| Critical illness | D016638 | — | — | — | — | — | — | 2 | 2 |
| Systemic inflammatory response syndrome | D018746 | EFO_1001478 | R65.10 | — | — | — | — | 2 | 2 |
| Dermatitis | D003872 | HP_0011123 | L30.9 | — | — | — | — | 1 | 1 |
| Lupus nephritis | D008181 | EFO_0005761 | — | — | — | — | — | 1 | 1 |
| Nephritis | D009393 | — | N05 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | — |
| INN | — |
| Description | — |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | — |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
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Variants
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Financial
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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