Linerixibat
Linerixibat is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Study first post date
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Commercial
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pruritus | D011537 | — | L29 | 3 | 2 | 1 | — | 1 | 7 |
| Cholestasis | D002779 | — | K83.1 | 3 | 2 | 1 | — | — | 6 |
| Biliary liver cirrhosis | D008105 | — | K74.3 | — | 2 | 2 | — | 1 | 5 |
| Cholangitis | D002761 | HP_0030151 | K83.0 | — | 1 | 1 | — | 1 | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 2 | 2 | — | — | — | 4 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 2 | — | — | — | 2 |
| Fibrosis | D005355 | — | — | — | 1 | — | — | — | 1 |
| Intrahepatic cholestasis | D002780 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Linerixibat |
| INN | linerixibat |
| Description | Linerixibat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | ileal bile acid transporter (IBAT) inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNC(CC(=O)O)CC(=O)O)c(OC)cc2[C@@H](c2ccccc2)N1 |
Identifiers
| PDB | — |
| CAS-ID | 1345982-69-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2387408 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 386012Z45S (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 151 documents
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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