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Drug ReportsLindane
Lindane
Gamene, Kwell, Scabene (lindane) is a small molecule pharmaceutical. Lindane was first approved as Kwell on 1982-01-01. It is used to treat lice infestations and scabies in the USA.
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FDA approval date
EMA approval date
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Study first post date
Last update post date
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Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Lindane
Tradename
Company
Number
Date
Products
KWELLReed And Carnrick PharmaceuticalsN-006309 DISCN1982-01-01
2 products
KWELLReed And Carnrick PharmaceuticalsN-010718 DISCN1982-01-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
lindaneANDA2011-12-13
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
lice infestations—D010373B85.2
scabies—D012532B86
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P03: Ectoparasiticides, incl. scabicides, insecticides and repellents
— P03A: Ectoparasiticides, incl. scabicides
— P03AB: Chlorine containing product ectoparasiticides
— P03AB02: Lindane
HCPCS
No data
Clinical
Clinical Trials
107 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postoperative painD010149—G89.18—1311115
PainD010146EFO_0003843R52———167
OsteoarthritisD010003EFO_0002506M15-M19——1315
NeoplasmsD009369—C80122115
AnesthesiaD000758——3——1—4
NauseaD009325—R11.0—112—3
HypertensionD006973EFO_0000537I10———123
Spinal stenosisD013130EFO_0007490M48.0———213
Low back painD017116—M54.5——1113
Knee osteoarthritisD020370EFO_0004616M17———3—3
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938—C95234——7
Breast neoplasmsD001943EFO_0003869C50113—16
LymphomaD008223—C85.9223——5
Precursor cell lymphoblastic leukemia-lymphomaD054198—C91.02—2——4
CarcinomaD002277—C80.0121——4
Multiple myelomaD009101—C90.0122——3
Healthy volunteers/patients———2—1——3
General anesthesiaD000768————1—23
Hodgkin diseaseD006689—C811—1——2
Lymphoid leukemiaD007945—C911—1——2
Show 19 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_0000340—11———2
Myeloid leukemia chronic-phaseD015466——11———2
Renal cell carcinomaD002292EFO_0000376——2———2
Male breast neoplasmsD018567———1———1
MastodyniaD059373EFO_1001366N64.4—1———1
Skin neoplasmsD012878EFO_0004198C44—1———1
MelanomaD008545———1———1
Cutaneous malignant melanomaD000096142———1———1
Overactive urinary bladderD053201EFO_1000781N32.81—1———1
Lice infestationsD010373—B85.2—1———1
Show 3 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-hodgkin lymphomaD008228—C85.92————2
RecurrenceD012008——2————2
Motor activityD009043EFO_0003940—1———12
Myelodysplastic syndromesD009190—D461————1
Myeloid leukemia acuteD015470—C92.01————1
Hematologic neoplasmsD019337——1————1
Prostatic neoplasmsD011471—C611————1
Castration-resistant prostatic neoplasmsD064129——1————1
Pancreatic neoplasmsD010190EFO_0003860C251————1
Myeloproliferative disordersD009196—D47.11————1
Show 47 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sleep initiation and maintenance disordersD007319—F51.01————33
Sleep wake disordersD012893—G47————33
SpasmD013035—M62.83————22
Hot flashesD019584——————22
FibromyalgiaD005356EFO_0005687M79.1————22
ParasomniasD020447—G47.5————22
HemorrhageD006470MP_0001914R58————11
Heart failureD006333EFO_0003144I50————11
Covid-19D000086382—U07.1————11
Coronavirus infectionsD018352EFO_0007224B34.2————11
Show 45 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLindane
INNlindane
Description
Beta-hexachlorocyclohexane is the beta-isomer of hexachlorocyclohexane. It has a role as a persistent organic pollutant. It is an organochlorine pesticide and a hexachlorocyclohexane.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl
Identifiers
PDB—
CAS-ID58-89-9
RxCUI—
ChEMBL IDCHEMBL15891
ChEBI ID32888
PubChem CID727
DrugBankDB00431
UNII ID59NEE7PCAB (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Lindane
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 5,051 documents
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Safety
Black-box Warning
Black-box warning for: Lindane
Adverse Events
Top Adverse Reactions
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166 adverse events reported
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