Lincomycin
Lincocin, Lincomycin (lincomycin) is a small molecule pharmaceutical. Lincomycin was first approved as Lincocin on 1982-01-01. It is used to treat pneumococcal infections and staphylococcal infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
EMA
Lincocin, Lincomycin (discontinued: Lincocin, Lincomycin)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| lincocin | New Drug Application | 2025-03-10 |
| lincomycin | ANDA | 2024-10-16 |
| lincomycin hydrochloride | ANDA | 2022-09-28 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| pneumococcal infections | EFO_0000772 | D011008 | J13 |
| staphylococcal infections | — | D013203 | A49.01 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J2010 | Injection, lincomycin hcl, up to 300 mg |
Clinical
Clinical Trials
154 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acne vulgaris | D000152 | EFO_0003894 | L70 | 8 | 2 | 10 | 16 | — | 35 |
| Infections | D007239 | EFO_0000544 | — | 2 | 3 | 6 | 6 | 6 | 21 |
| Staphylococcal infections | D013203 | — | A49.01 | — | 2 | 3 | 3 | 3 | 10 |
| Bacterial vaginosis | D016585 | EFO_0003932 | — | 1 | 1 | 3 | 4 | 1 | 10 |
| Bacterial infections | D001424 | — | A49 | 3 | — | 1 | 2 | 3 | 9 |
| Surgical wound infection | D013530 | — | — | — | 1 | — | 6 | 2 | 9 |
| Communicable diseases | D003141 | — | — | — | — | 3 | 2 | 3 | 8 |
| Abscess | D000038 | EFO_0003030 | — | — | 1 | — | 1 | 3 | 5 |
| Wound infection | D014946 | — | — | — | — | — | 4 | — | 4 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | 2 | 1 | 3 |
Show 45 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | 1 | — | 3 | 4 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | — | 1 | — | 3 | 4 |
| Malaria | D008288 | EFO_0001068 | B54 | — | 1 | 2 | — | — | 3 |
| Appendicitis | D001064 | EFO_0007149 | K37 | — | 1 | 1 | — | 1 | 3 |
| Covid-19 | D000086382 | — | U07.1 | — | 1 | 1 | — | 1 | 2 |
| Methicillin-resistant staphylococcus aureus | D055624 | — | — | — | — | 2 | — | — | 2 |
| Bacterial skin diseases | D017192 | — | — | — | — | 1 | — | 1 | 2 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | — | 1 | — | 1 | 2 |
| Nasal obstruction | D015508 | — | — | — | — | 1 | — | — | 1 |
| Nasal surgical procedures | D059747 | — | — | — | — | 1 | — | — | 1 |
Show 16 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | — | 1 | — | — | — | 1 |
| Head and neck neoplasms | D006258 | — | — | — | 1 | — | — | — | 1 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | — | 1 | — | — | — | 1 |
| Glucose intolerance | D018149 | HP_0000833 | R73.03 | — | 1 | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | — | 1 | — | — | — | 1 |
| Exanthema | D005076 | — | — | — | 1 | — | — | — | 1 |
| Female infertility | D007247 | EFO_0008560 | N97 | — | 1 | — | — | — | 1 |
| Non-small-cell lung carcinoma | D002289 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Jaw fractures | D007572 | — | — | 1 | — | — | — | — | 1 |
| Mandibular fractures | D008337 | — | S02.6 | 1 | — | — | — | — | 1 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aids-related opportunistic infections | D017088 | — | — | — | — | — | — | 3 | 3 |
| Staphylococcus aureus | D013211 | NCBITaxon_1280 | — | — | — | — | — | 2 | 2 |
| Hidradenitis suppurativa | D017497 | — | L73.2 | — | — | — | — | 2 | 2 |
| Toxoplasmosis | D014123 | EFO_0007517 | B58 | — | — | — | — | 2 | 2 |
| Cerebral toxoplasmosis | D016781 | EFO_0007200 | B58.2 | — | — | — | — | 2 | 2 |
| Encephalitis | D004660 | — | — | — | — | — | — | 2 | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 1 | 1 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | — | — | — | 1 | 1 |
Show 48 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Lincomycin |
| INN | lincomycin |
| Description | Lincomycin is a carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis. It has a role as an antimicrobial agent and a bacterial metabolite. It is a carbohydrate-containing antibiotic, a S-glycosyl compound, a monocarboxylic acid amide, a pyrrolidinecarboxamide and a L-proline derivative. |
| Classification | Small molecule |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)N(C)C1 |
Identifiers
| PDB | — |
| CAS-ID | 154-21-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1447 |
| ChEBI ID | 6472 |
| PubChem CID | 3000540 |
| DrugBank | DB01627 |
| UNII ID | BOD072YW0F (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Lincomycin
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 9,262 documents
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Safety
Black-box Warning
Black-box warning for: Lincocin, Lincomycin, Lincomycin hydrochloride
Adverse Events
Top Adverse Reactions
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256 adverse events reported
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