Lincomycin
Lincocin, Lincomycin (lincomycin) is a small molecule pharmaceutical. Lincomycin was first approved as Lincocin on 1982-01-01. It is used to treat pneumococcal infections and staphylococcal infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
EMA
Lincocin, Lincomycin (discontinued: Lincocin, Lincomycin)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| lincocin | New Drug Application | 2024-06-07 |
| lincomycin | ANDA | 2024-10-16 |
| lincomycin hydrochloride | ANDA | 2022-09-28 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| pneumococcal infections | EFO_0000772 | D011008 | J13 |
| staphylococcal infections | — | D013203 | A49.01 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J2010 | Injection, lincomycin hcl, up to 300 mg |
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Staphylococcal infections | D013203 | — | A49.01 | — | — | — | 1 | — | 1 |
| Bacteremia | D016470 | EFO_0003033 | R78.81 | — | — | — | 1 | — | 1 |
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
| Bacterial infections | D001424 | — | A49 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Aortic valve disease | D000082862 | — | — | — | — | — | — | 1 | 1 |
| Aortic valve stenosis | D001024 | HP_0001650 | — | — | — | — | — | 1 | 1 |
| Pathologic constriction | D003251 | — | — | — | — | — | — | 1 | 1 |
| Calcinosis | D002114 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Lincomycin |
| INN | lincomycin |
| Description | Lincomycin is a carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis. It has a role as an antimicrobial agent and a bacterial metabolite. It is a carbohydrate-containing antibiotic, a S-glycosyl compound, a monocarboxylic acid amide, a pyrrolidinecarboxamide and a L-proline derivative. |
| Classification | Small molecule |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)N(C)C1 |
Identifiers
| PDB | — |
| CAS-ID | 154-21-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1447 |
| ChEBI ID | 6472 |
| PubChem CID | 3000540 |
| DrugBank | DB01627 |
| UNII ID | BOD072YW0F (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Lincomycin
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 8,582 documents
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Safety
Black-box Warning
Black-box warning for: Lincocin, Lincomycin, Lincomycin hydrochloride
Adverse Events
Top Adverse Reactions
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309 adverse events reported
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