Ligelizumab
Ligelizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against Immunoglobulin heavy constant epsilon.
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FDA approval date
EMA approval date
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Study first post date
Last update post date
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Completion date
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Commercial
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Clinical
Clinical Trials
20 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic urticaria | D000080223 | — | L50.8 | 1 | 3 | 5 | — | 1 | 10 |
| Urticaria | D014581 | EFO_0005531 | L50 | 1 | 3 | 3 | — | 1 | 8 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | 2 | 3 | 2 | — | — | 6 |
| Peanut hypersensitivity | D021183 | EFO_0007425 | — | — | 1 | 1 | — | — | 2 |
| Chronic inducible urticaria | D000094482 | — | L50.4 | — | — | 1 | — | — | 1 |
| Food hypersensitivity | D005512 | EFO_1001890 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 1 | 4 | — | — | — | 4 |
| Bronchiolitis obliterans syndrome | D000092122 | — | D89.811 | — | 1 | — | — | — | 1 |
| Bullous pemphigoid | D010391 | EFO_0007187 | L12 | — | 1 | — | — | — | 1 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 1 | — | — | — | 1 |
| Skin diseases | D012871 | — | L00-L99 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cold urticaria | D000096703 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ligelizumab |
| INN | ligelizumab |
| Description | Ligelizumab (humanized mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | 6UQR |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109457 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | L8LE0L691T (ChemIDplus, GSRS) |
Target
Agency Approved
IGHE
IGHE
Organism
Homo sapiens
Gene name
IGHE
Gene synonyms
NCBI Gene ID
—
Protein name
Immunoglobulin heavy constant epsilon
Protein synonyms
Ig epsilon chain C region, Ig epsilon chain C region ND
Uniprot ID
Mouse ortholog
—
—
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 326 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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