Lidofenin
Technescan (lidofenin) is a small molecule pharmaceutical. Lidofenin was first approved as Technescan hida on 1986-10-31.
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Commercial
Therapeutic Areas
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FDA
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| technescan hdp | New Drug Application | 2022-12-20 |
| technescan mag3 | New Drug Application | 2022-12-13 |
| technescan pyp | New Drug Application | 2024-06-07 |
Indications
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Agency Specific
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Clinical
Clinical Trials
20 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | — | — | 1 | 1 | 2 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | 1 | — | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | 1 | — | 1 |
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | — | — | — | 1 | — | 1 |
| Beta-thalassemia | D017086 | Orphanet_848 | D56.1 | — | — | — | 1 | — | 1 |
| Thalassemia | D013789 | EFO_1001996 | D56 | — | — | — | 1 | — | 1 |
| Hemochromatosis | D006432 | EFO_1000642 | E83.11 | — | — | — | 1 | — | 1 |
| Hemosiderosis | D006486 | — | — | — | — | — | 1 | — | 1 |
| Abdominal pain | D015746 | EFO_0003766 | R10.9 | — | — | — | 1 | — | 1 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hematologic neoplasms | D019337 | — | — | — | 1 | 1 | — | — | 2 |
| Neoplasms | D009369 | — | C80 | — | — | 1 | — | — | 1 |
| Hematopoietic stem cell transplantation | D018380 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Recurrence | D012008 | — | — | — | 1 | — | — | — | 1 |
| Graft vs host disease | D006086 | — | D89.81 | — | 1 | — | — | — | 1 |
| Peripheral blood stem cell transplantation | D036102 | — | — | — | 1 | — | — | — | 1 |
| Lymphocyte transfusion | D017710 | — | — | — | 1 | — | — | — | 1 |
| Leukemia | D007938 | — | C95 | — | 1 | — | — | — | 1 |
| Lymphoid leukemia | D007945 | — | C91 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | — | — | — | 2 | 2 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | — | — | 2 | 2 |
| Liver failure | D017093 | — | K72.9 | — | — | — | — | 2 | 2 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | — | — | — | — | 1 | 1 |
| Fatty liver | D005234 | EFO_0003934 | — | — | — | — | — | 1 | 1 |
| Cholecystitis | D002764 | — | K81 | — | — | — | — | 1 | 1 |
| Dyskinesias | D020820 | — | G24 | — | — | — | — | 1 | 1 |
| Biliary dyskinesia | D001657 | EFO_0007169 | — | — | — | — | — | 1 | 1 |
| Carcinoma | D002277 | — | C80.0 | — | — | — | — | 1 | 1 |
| Cholangiocarcinoma | D018281 | — | C22.1 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Lidofenin |
| INN | lidofenin |
| Description | Lidofenin is an amino acid amide. |
| Classification | Small molecule |
| Drug class | diagnostic aids ((phenylcarbamoyl) methyl iminodiacetic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cccc(C)c1NC(=O)CN(CC(=O)O)CC(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 59160-29-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1400608 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | EK22QV7701 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
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Adverse Events
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105 adverse events reported
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