Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TWIRLA | Agile Therapeutics | N-204017 RX | 2020-02-14 | 1 products, RLD, RS |
BALCOLTRA | Avion Pharmaceuticals | N-208612 RX | 2018-01-09 | 1 products, RLD, RS |
TYBLUME | Exeltis | N-209405 RX | 2020-03-30 | 1 products, RLD, RS |
LOSEASONIQUE | Teva | N-022262 RX | 2008-10-24 | 1 products |
QUARTETTE | Teva | N-204061 RX | 2013-03-28 | 1 products, RLD, RS |
SEASONALE | Teva | N-021544 RX | 2003-09-05 | 1 products, RLD, RS |
SEASONIQUE | Teva | N-021840 RX | 2006-05-25 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
KYLEENA | Bayer | N-208224 RX | 2016-09-16 | 1 products, RLD, RS |
MIRENA | Bayer | N-021225 RX | 2000-12-06 | 1 products, RLD, RS |
SKYLA | Bayer | N-203159 RX | 2013-01-09 | 1 products, RLD, RS |
PLAN B ONE-STEP | Foundation Consumer Healthcare | N-021998 OTC | 2009-07-10 | 1 products, RLD, RS |
LILETTA | Medicines360 | N-206229 RX | 2015-02-26 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
afirmelle | ANDA | 2025-08-01 |
after banger | ANDA | 2025-04-04 |
aftera | NDA authorized generic | 2023-01-31 |
afterpill | ANDA | 2025-05-01 |
afterplan | ANDA | 2018-10-26 |
altavera | ANDA | 2023-03-02 |
amazon basic care levonorgestrel | ANDA | 2025-04-04 |
amethia | ANDA | 2024-03-01 |
amethyst | ANDA | 2022-01-31 |
ashlyna | ANDA | 2023-12-10 |
Expiration | Code | ||
---|---|---|---|
LEVONORGESTREL, LILETTA, MEDICINES360 | |||
2026-06-29 | I-917 |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Levonorgestrel, Liletta, Medicines360 | |||
11571328 | 2040-09-07 | DP | |
10028858 | 2034-03-22 | DP | U-2348 |
11090186 | 2033-10-24 | U-2348 | |
Levonorgestrel, Kyleena, Bayer Hlthcare | |||
10561524 | 2029-09-16 | U-2948 | |
11850182 | 2029-09-14 | DP | U-3819 |
11628088 | 2027-02-07 | DP | |
Ethinyl Estradiol / Levonorgestrel, Quartette, Teva Branded Pharm | |||
8415332 | 2029-03-11 | DP | |
8450299 | 2025-10-07 | U-1 | |
Ethinyl Estradiol / Levonorgestrel, Loseasonique, Teva Branded Pharm | |||
7855190 | 2028-12-05 | U-1 | |
Ethinyl Estradiol / Levonorgestrel, Twirla, Agile | |||
8246978 | 2028-08-26 | DP | |
8747888 | 2028-07-10 | DP | |
9050348 | 2028-07-10 | DP | |
Ethinyl Estradiol / Levonorgestrel, Balcoltra, Avion Pharms | |||
7838042 | 2027-06-01 | DP | U-3251 |
Ethinyl Estradiol / Levonorgestrel, Seasonique, Teva Branded Pharm | |||
7320969 | 2024-01-30 | U-828 |
Code | Description |
---|---|
J7296 | Levonorgestrel-releasing intrauterine contraceptive system, (kyleena), 19.5 mg |
J7297 | Levonorgestrel-releasing intrauterine contraceptive system (liletta), 52 mg |
J7298 | Levonorgestrel-releasing intrauterine contraceptive system (mirena), 52 mg |
J7301 | Levonorgestrel-releasing intrauterine contraceptive system (skyla), 13.5 mg |
J7306 | Levonorgestrel (contraceptive) implant system, including implants and supplies |
S4981 | Insertion of levonorgestrel-releasing intrauterine system |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Contraception | D003267 | — | — | 15 | 16 | 32 | 32 | 60 | 153 |
Neoplasms | D009369 | — | C80 | 48 | 19 | 4 | 2 | 23 | 82 |
Healthy volunteers/patients | — | — | — | 68 | 4 | 3 | 1 | 6 | 79 |
Lymphoma | D008223 | — | C85.9 | 29 | 28 | 4 | 1 | 8 | 58 |
Obesity | D009765 | EFO_0001073 | E66.9 | 5 | 2 | 1 | 4 | 22 | 33 |
Hemorrhage | D006470 | MP_0001914 | R58 | 3 | 5 | 1 | 8 | 16 | 30 |
Hiv infections | D015658 | EFO_0000764 | B20 | 9 | 2 | 1 | 1 | 16 | 29 |
Hiv | D006678 | — | O98.7 | 4 | 3 | 1 | 4 | 14 | 26 |
Emergencies | D004630 | — | — | 1 | 2 | 4 | 8 | 13 | 26 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 6 | 1 | — | 1 | 17 | 25 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 5 | 5 | 3 | — | 27 | 38 |
B-cell lymphoma | D016393 | — | — | 20 | 14 | 1 | — | 6 | 36 |
Non-small-cell lung carcinoma | D002289 | — | — | 13 | 19 | 3 | — | 6 | 34 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 6 | 16 | 2 | — | 7 | 27 |
Lung neoplasms | D008175 | — | C34.90 | 5 | 9 | 3 | — | 11 | 27 |
Carcinoma | D002277 | — | C80.0 | 8 | 9 | 5 | — | 7 | 25 |
Prostatic neoplasms | D011471 | — | C61 | 6 | 6 | 5 | — | 7 | 22 |
Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | 14 | 6 | — | 3 | 22 |
Leukemia | D007938 | — | C95 | 13 | 11 | 1 | — | 1 | 21 |
Hyperplasia | D006965 | EFO_0000536 | — | 1 | 14 | 6 | — | 5 | 21 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myeloid leukemia acute | D015470 | — | C92.0 | 8 | 9 | — | — | 1 | 15 |
Glioblastoma | D005909 | EFO_0000515 | — | 8 | 6 | — | — | 1 | 12 |
Suicide | D013405 | — | — | — | 1 | — | — | 11 | 12 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | 5 | 1 | — | — | 5 | 11 |
Adenomyosis | D062788 | EFO_1001757 | N80.0 | 1 | 1 | — | — | 9 | 11 |
Myeloid leukemia | D007951 | — | C92 | 4 | 6 | — | — | 1 | 10 |
Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | — | — | 9 | 10 |
Glioma | D005910 | EFO_0000520 | — | 6 | 3 | — | — | 1 | 9 |
Weight loss | D015431 | — | — | — | 1 | — | — | 8 | 9 |
Squamous cell carcinoma of head and neck | D000077195 | — | — | 2 | 4 | — | — | 4 | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | — | — | — | 13 | 15 |
Lung diseases | D008171 | EFO_0003818 | J98.4 | 2 | — | — | — | 8 | 10 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | — | — | — | 9 | 10 |
Multiple sclerosis | D009103 | EFO_0003885 | G35 | 2 | — | — | — | 6 | 8 |
Asthma | D001249 | EFO_0000270 | J45 | 2 | — | — | — | 6 | 8 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | 1 | — | — | — | 7 | 8 |
Sclerosis | D012598 | — | — | 2 | — | — | — | 5 | 7 |
Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | — | — | — | 6 | 7 |
Fibrosis | D005355 | — | — | 2 | — | — | — | 4 | 6 |
Drug interactions | D004347 | — | — | 5 | — | — | — | 1 | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Dementia | D003704 | EFO_0003862 | F03 | — | — | — | — | 13 | 13 |
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | — | — | 12 | 12 |
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | — | — | — | 11 | 11 |
Anxiety | D001007 | EFO_0005230 | F41.1 | — | — | — | — | 10 | 10 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | — | 9 | 9 |
Exercise | D015444 | EFO_0000483 | — | — | — | — | — | 9 | 9 |
Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 8 | 8 |
Suicidal ideation | D059020 | EFO_0004320 | R45.851 | — | — | — | — | 8 | 8 |
Attempted suicide | D013406 | EFO_0004321 | T14.91 | — | — | — | — | 8 | 8 |
Autism spectrum disorder | D000067877 | — | F84.0 | — | — | — | — | 8 | 8 |
Drug common name | Levonorgestrel |
INN | levonorgestrel |
Description | Norgestrel is a progestin which is used in birth control pills sold under the brand name Ovral in combination with the estrogen ethinylestradiol and Opill by itself. It is also used in menopausal hormone therapy. It is taken by mouth.
|
Classification | Small molecule |
Drug class | estrogens; progestins |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@@]21CC |
PDB | — |
CAS-ID | 6533-00-2 |
RxCUI | — |
ChEMBL ID | CHEMBL1389 |
ChEBI ID | 6443 |
PubChem CID | 16051930 |
DrugBank | DB00367 |
UNII ID | 5W7SIA7YZW (ChemIDplus, GSRS) |