Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Schizophrenia | D012559 | EFO_0000692 | F20 | — | 1 | 1 | 1 | 2 | 5 |
Neoplasms | D009369 | — | C80 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Psychotic disorders | D011618 | — | F20.81 | — | — | 1 | — | 1 | 2 |
Dementia | D003704 | EFO_0003862 | F03 | — | — | 1 | — | — | 1 |
Psychophysiologic disorders | D011602 | — | F45.9 | — | — | 1 | — | — | 1 |
Depression | D003863 | — | F33.9 | — | — | 1 | — | — | 1 |
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | — | 1 | — | — | 1 |
Somatoform disorders | D013001 | — | F45 | — | — | 1 | — | — | 1 |
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Recurrence | D012008 | — | — | — | — | — | — | 1 | 1 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
Emergencies | D004630 | — | — | — | — | — | — | 1 | 1 |
Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 1 | 1 |
Delirium | D003693 | — | R41.0 | — | — | — | — | 1 | 1 |
Psychomotor agitation | D011595 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Levomepromazine |
INN | levomepromazine |
Description | Methotrimeprazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist, a serotonergic antagonist, a cholinergic antagonist, a non-narcotic analgesic, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor and an anticoronaviral agent. It is a member of phenothiazines and a tertiary amine. It derives from a hydride of a 10H-phenothiazine. |
Classification | Small molecule |
Drug class | Typical antipsychotic |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | COc1ccc2c(c1)N(C[C@H](C)CN(C)C)c1ccccc1S2 |
PDB | — |
CAS-ID | 60-99-1 |
RxCUI | — |
ChEMBL ID | CHEMBL1764 |
ChEBI ID | 6838 |
PubChem CID | 72287 |
DrugBank | DB01403 |
UNII ID | 9G0LAW7ATQ (ChemIDplus, GSRS) |