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Drug ReportsLevomepromazine
Levomepromazine
Levoprome (levomepromazine) is a small molecule pharmaceutical. Levomepromazine was first approved as Levoprome on 1982-01-01.
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Events Timeline
5D
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Levomepromazine
Tradename
Company
Number
Date
Products
LEVOPROMEImmunexN-015865 DISCN1982-01-01
1 products
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FDA
EMA
No data
Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N05: Psycholeptics
N05A: Antipsychotics
N05AA: Phenothiazines with aliphatic side-chain, antipsychotics
N05AA02: Levomepromazine
HCPCS
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SchizophreniaD012559EFO_0000692F2011125
NeoplasmsD009369C8011
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Psychotic disordersD011618F20.81112
DementiaD003704EFO_0003862F0311
Psychophysiologic disordersD011602F45.911
DepressionD003863F33.911
Anxiety disordersD001008EFO_0006788F41.111
Somatoform disordersD013001F4511
Mental disordersD001523EFO_0000677F91.911
Indications Phases 2
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Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
RecurrenceD01200811
Type 2 diabetes mellitusD003924EFO_0001360E1111
EmergenciesD00463011
Bipolar disorderD001714EFO_0000289F30.911
DeliriumD003693R41.011
Psychomotor agitationD01159511
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLevomepromazine
INNlevomepromazine
Description
Methotrimeprazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist, a serotonergic antagonist, a cholinergic antagonist, a non-narcotic analgesic, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor and an anticoronaviral agent. It is a member of phenothiazines and a tertiary amine. It derives from a hydride of a 10H-phenothiazine.
Classification
Small molecule
Drug classTypical antipsychotic
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Structure (InChI/SMILES or Protein Sequence)
COc1ccc2c(c1)N(C[C@H](C)CN(C)C)c1ccccc1S2
Identifiers
PDB
CAS-ID60-99-1
RxCUI
ChEMBL IDCHEMBL1764
ChEBI ID6838
PubChem CID72287
DrugBankDB01403
UNII ID9G0LAW7ATQ (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,465 adverse events reported
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