Levocetirizine
Levocetirizine, Xyzal (levocetirizine) is a small molecule pharmaceutical. Levocetirizine was first approved as Xyzal on 2007-05-25. It is used to treat allergic rhinitis perennial, allergic rhinitis seasonal, and urticaria in the USA. The pharmaceutical is active against histamine H1 receptor.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Levocetirizine, Xyzal (discontinued: Levocetirizine, Xyzal)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 12 hour allergy d | ANDA | 2020-09-03 |
| 24 hour allergy | New Drug Application | 2024-04-01 |
| 24hr allergy relief | ANDA | 2024-10-22 |
| all day | ANDA | 2020-06-18 |
| all day allergy | ANDA | 2023-03-20 |
| all day allergy d | ANDA | 2020-08-31 |
| all day allergy relief | ANDA | 2024-08-05 |
| all day allergy relief d | ANDA | 2018-12-06 |
| all day allergy-d | ANDA | 2022-06-13 |
| allergy | ANDA | 2024-06-03 |
Show 143 more
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent | Expires | Flag | FDA Information |
|---|---|---|---|
| Levocetirizine Dihydrochloride, Xyzal Allergy 24hr, Chattem Sanofi | |||
| 8633194 | 2027-10-16 | DP | |
HCPCS
No data
Clinical
Clinical Trials
195 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rhinitis | D012220 | EFO_0008521 | J31 | 4 | 10 | 23 | 29 | 12 | 78 |
| Allergic rhinitis | D065631 | — | J30.9 | 2 | 10 | 21 | 29 | 11 | 73 |
| Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | — | 7 | 5 | 13 | 5 | 30 |
| Urticaria | D014581 | EFO_0005531 | L50 | 2 | 2 | 9 | 9 | 2 | 23 |
| Allergic rhinitis perennial | D012221 | EFO_1001417 | J30.89 | 1 | — | 9 | 10 | 1 | 21 |
| Healthy volunteers/patients | — | — | — | 12 | — | 1 | 2 | 2 | 17 |
| Chronic urticaria | D000080223 | — | L50.8 | 1 | 2 | 6 | 8 | — | 16 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | 6 | 1 | — | 3 | 1 | 11 |
| Asthma | D001249 | EFO_0000270 | J45 | — | 2 | 4 | 3 | — | 8 |
| Dermatitis | D003872 | HP_0011123 | L30.9 | 1 | 1 | 3 | 1 | 1 | 7 |
Show 21 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Conjunctivitis | D003231 | HP_0000509 | H10 | — | 2 | 5 | — | — | 6 |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | 2 | 5 | — | — | 6 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | 1 | — | — | 4 |
| Vasomotor rhinitis | D012223 | EFO_0007533 | J30.0 | — | — | 1 | — | 1 | 2 |
| Seasonal affective disorder | D016574 | — | — | — | 1 | 1 | — | — | 2 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | 1 | 1 | — | — | 2 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | — | 1 | — | — | 1 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | — | — | 1 | — | — | 1 |
| Head and neck neoplasms | D006258 | — | — | — | — | 1 | — | — | 1 |
| Esophageal neoplasms | D004938 | — | C15 | — | — | 1 | — | — | 1 |
Show 5 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis b | D006509 | — | — | — | 4 | — | — | — | 4 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | — | 4 | — | — | — | 4 |
| Hepatitis | D006505 | HP_0012115 | K75.9 | — | 4 | — | — | — | 4 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | — | 4 | — | — | — | 4 |
| Disease | D004194 | EFO_0000408 | R69 | 1 | 1 | — | — | 2 | 3 |
| Syndrome | D013577 | — | — | — | 2 | — | — | 1 | 3 |
| Nephrotic syndrome | D009404 | EFO_0004255 | N04 | — | 2 | — | — | — | 2 |
| Nephrosis | D009401 | — | — | — | 2 | — | — | — | 2 |
| Colorectal neoplasms | D015179 | — | — | — | 1 | — | — | — | 1 |
| Hepatitis d | D003699 | EFO_0007304 | — | — | 1 | — | — | — | 1 |
Show 19 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | 4 | — | — | — | — | 4 |
| Fasting | D005215 | EFO_0002756 | — | 2 | — | — | — | — | 2 |
| Chronic progressive multiple sclerosis | D020528 | EFO_0003840 | — | 1 | — | — | — | — | 1 |
| Prostatitis | D011472 | EFO_0003830 | N41 | 1 | — | — | — | — | 1 |
| Pelvic pain | D017699 | — | — | 1 | — | — | — | — | 1 |
| Migraine disorders | D008881 | EFO_0003821 | G43 | 1 | — | — | — | — | 1 |
| Larva migrans | D007815 | EFO_0007391 | B76.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | — | 1 | 1 |
| Diarrhea | D003967 | HP_0002014 | R19.7 | — | — | — | — | 1 | 1 |
| Cognition | D003071 | EFO_0003925 | — | — | — | — | — | 1 | 1 |
| Actinic keratosis | D055623 | — | L57.0 | — | — | — | — | 1 | 1 |
| Keratosis | D007642 | — | — | — | — | — | — | 1 | 1 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | — | — | 1 | 1 |
| Peripheral nervous system diseases | D010523 | HP_0009830 | G64 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Levocetirizine |
| INN | levocetirizine |
| Description | 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid is a diarylmethane. |
| Classification | Small molecule |
| Drug class | Second generation antihistamines |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)COCCN1CCN([C@H](c2ccccc2)c2ccc(Cl)cc2)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 130018-77-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201191 |
| ChEBI ID | — |
| PubChem CID | 1549000 |
| DrugBank | DB06282 |
| UNII ID | 6U5EA9RT2O (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Levocetirizine
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 5,774 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
53,002 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use