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Drug ReportsLevobetaxolol
Levobetaxolol
Betaxon (levobetaxolol) is a small molecule pharmaceutical. Levobetaxolol was first approved as Betaxon on 2000-02-23. It is used to treat ocular hypertension and open-angle glaucoma in the USA. The pharmaceutical is active against beta-1 adrenergic receptor. In addition, it is known to target beta-2 adrenergic receptor.
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FDA approval date
EMA approval date
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Study first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
eye diseasesD005128
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Levobetaxolol hydrochloride
Tradename
Company
Number
Date
Products
BETAXONAlcon ResearchN-021114 DISCN2000-02-23
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
ocular hypertensionEFO_1001069D009798H40.0
open-angle glaucomaEFO_0004190D005902H40.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypertensionD006973EFO_0000537I10——2——2
Ocular hypertensionD009798EFO_1001069H40.0——2——2
GlaucomaD005901EFO_0000516H40——2——2
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLevobetaxolol
INNlevobetaxolol
Description
(S)-betaxolol is the (S)-enantiomer of betaxolol. It is an enantiomer of a (R)-betaxolol.
Classification
Small molecule
Drug classbeta-blockers (propranolol type)
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Structure (InChI/SMILES or Protein Sequence)
CC(C)NC[C@H](O)COc1ccc(CCOCC2CC2)cc1
Identifiers
PDB—
CAS-ID116209-55-3
RxCUI—
ChEMBL IDCHEMBL1201274
ChEBI ID59254
PubChem CID60657
DrugBankDB00195
UNII ID75O9XHA4TU (ChemIDplus, GSRS)
Target
Agency Approved
ADRB1
ADRB1
Organism
Homo sapiens
Gene name
ADRB1
Gene synonyms
ADRB1R, B1AR
NCBI Gene ID
153
Protein name
beta-1 adrenergic receptor
Protein synonyms
adrenergic, beta-1-, receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor
Uniprot ID
Q9UKG8
Mouse ortholog
Adrb1 (11554)
beta-1 adrenergic receptor (P34971)
Alternate
ADRB2
ADRB2
Organism
Homo sapiens
Gene name
ADRB2
Gene synonyms
ADRB2R, B2AR
NCBI Gene ID
154
Protein name
beta-2 adrenergic receptor
Protein synonyms
adrenergic, beta-2-, receptor, surface, adrenoceptor beta 2 surface, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, catecholamine receptor
Uniprot ID
Q9UMZ5
Mouse ortholog
Adrb2 (11555)
beta-2 adrenergic receptor (Q8BH38)
Variants
No data
Financial
No data
Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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