Therapeutic Area | MeSH |
---|---|
nervous system diseases | D009422 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
SPRITAM | Aprecia Pharmaceuticals | N-207958 RX | 2015-07-31 | 4 products, RLD, RS |
LEVETIRACETAM IN SODIUM CHLORIDE | HQ Specialty Pharma | N-202543 RX | 2011-11-09 | 3 products, RLD, RS |
KEPPRA | UCB | N-021035 RX | 1999-11-30 | 4 products, RLD |
KEPPRA | UCB | N-021505 RX | 2003-07-15 | 1 products, RLD, RS |
KEPPRA | UCB | N-021872 RX | 2006-07-31 | 1 products, RLD, RS |
KEPPRA XR | UCB | N-022285 RX | 2008-09-12 | 2 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
elepsia xr | New Drug Application | 2021-01-06 |
elepsia xr 1000 mg elepsia xr 1500 mg | New Drug Application | 2024-03-25 |
keppra | New Drug Application | 2024-04-22 |
keppra keppra | 2009-05-11 | |
keppra xr | 2009-05-21 | |
levetiracetam | ANDA | 2025-03-25 |
levetiracetam er | ANDA | 2025-01-22 |
levetiracetam extended-release | ANDA | 2009-08-15 |
levetiracetam in sodium chloride | ANDA | 2024-04-30 |
levetiracetam levetiracetam | ANDA | 2024-08-01 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
epilepsy | EFO_0000474 | D004827 | G40.9 |
juvenile myoclonic epilepsy | — | D020190 | G40.B |
partial epilepsies | EFO_0004263 | D004828 | — |
tonic-clonic epilepsy | EFO_0007262 | D004830 | — |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Levetiracetam, Spritam, Aprecia Pharms | |||
9339489 | 2034-03-14 | DP | U-1850 |
9669009 | 2034-03-14 | U-1850, U-2021, U-2022 | |
11160786 | 2034-03-14 | DP | |
Levetiracetam, Keppra, Ucb Inc | |||
8802142 | 2031-06-07 | DP | |
Levetiracetam, Keppra Xr, Ucb Inc | |||
7858122 | 2028-09-17 | DP | |
Levetiracetam, Elepsia Xr, Tripoint | |||
8431156 | 2027-10-31 | DP | |
8470367 | 2027-10-31 | DP | |
8163306 | 2027-09-03 | DP | |
8425938 | 2026-02-22 | DP | |
8535717 | 2026-02-22 | DP |
Code | Description |
---|---|
J1953 | Injection, levetiracetam, 10 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Epilepsy | D004827 | EFO_0000474 | G40.9 | 5 | 17 | 42 | 27 | 35 | 123 |
Seizures | D012640 | — | G40.4 | 8 | 19 | 29 | 16 | 17 | 82 |
Partial epilepsies | D004828 | EFO_0004263 | — | — | 2 | 9 | 10 | 1 | 22 |
Status epilepticus | D013226 | EFO_0008526 | G41 | — | 4 | 4 | 2 | 5 | 15 |
Healthy volunteers/patients | — | — | — | 10 | — | — | 1 | 2 | 13 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | — | 2 | 3 | 3 | 3 | 11 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 7 | 1 | 1 | 1 | 9 |
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 5 | — | 3 | — | 8 |
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 1 | 3 | 3 | 7 |
Stroke | D020521 | EFO_0000712 | I63.9 | 1 | — | 2 | 2 | 1 | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Generalized epilepsy | D004829 | — | — | — | — | 6 | — | 1 | 7 |
Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | 4 | 1 | — | 1 | 6 |
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | 2 | 1 | — | — | 3 |
Post-traumatic epilepsy | D004834 | — | — | — | 1 | 2 | — | — | 3 |
Dementia | D003704 | EFO_0003862 | F03 | — | 1 | 1 | — | — | 2 |
Depression | D003863 | — | F33.9 | — | — | 1 | — | 1 | 2 |
Reflex epilepsy | D020195 | EFO_1001146 | — | — | 2 | 1 | — | — | 2 |
Complex partial epilepsy | D017029 | EFO_1000877 | — | — | 1 | 1 | — | — | 2 |
Tardive dyskinesia | D000071057 | — | G24.01 | — | 1 | 1 | — | — | 2 |
Tonic-clonic epilepsy | D004830 | EFO_0007262 | — | — | — | 2 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Central nervous system neoplasms | D016543 | — | — | 1 | 3 | — | — | 3 | 6 |
Psychotic disorders | D011618 | — | F20.81 | — | 5 | — | — | 1 | 6 |
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | 5 | — | — | 1 | 6 |
Nervous system neoplasms | D009423 | — | — | 1 | 3 | — | — | 2 | 5 |
Neoplasms | D009369 | — | C80 | — | 1 | — | — | 3 | 4 |
Leukemia | D007938 | — | C95 | — | 3 | — | — | 1 | 4 |
Myeloid leukemia acute | D015470 | — | C92.0 | — | 3 | — | — | 1 | 4 |
Myelodysplastic syndromes | D009190 | — | D46 | — | 2 | — | — | 1 | 3 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | — | 2 | — | — | 1 | 3 |
Brain diseases | D001927 | — | G93.40 | — | 1 | — | — | 2 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sarcoma | D012509 | — | — | 1 | — | — | — | 1 | 2 |
Ewing sarcoma | D012512 | EFO_0000173 | — | 1 | — | — | — | 1 | 2 |
Malnutrition | D044342 | EFO_0008572 | E40-E46 | 1 | — | — | — | — | 1 |
Aphasia | D001037 | — | R47.01 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Premenstrual dysphoric disorder | D065446 | — | F32.81 | — | — | — | — | 2 | 2 |
Acute kidney injury | D058186 | — | N17 | — | — | — | — | 1 | 1 |
Pharmacokinetics | D010599 | — | — | — | — | — | — | 1 | 1 |
Financial stress | D000086522 | — | — | — | — | — | — | 1 | 1 |
Germ cell and embryonal neoplasms | D009373 | — | — | — | — | — | — | 1 | 1 |
Medulloblastoma | D008527 | — | — | — | — | — | — | 1 | 1 |
Retinoblastoma | D012175 | — | — | — | — | — | — | 1 | 1 |
Rhabdoid tumor | D018335 | — | — | — | — | — | — | 1 | 1 |
Rhabdomyosarcoma | D012208 | — | — | — | — | — | — | 1 | 1 |
Primitive neuroectodermal tumors | D018242 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Levetiracetam |
INN | levetiracetam |
Description | Levetiracetam is a pyrrolidinone and carboxamide that is N-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the S enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine. It has a role as an anticonvulsant, an environmental contaminant and a xenobiotic. |
Classification | Small molecule |
Drug class | nootropic agents (learning, cognitive enhancers), piracetam type |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC[C@@H](C(N)=O)N1CCCC1=O |
PDB | — |
CAS-ID | 102767-28-2 |
RxCUI | — |
ChEMBL ID | CHEMBL1286 |
ChEBI ID | 6437 |
PubChem CID | 5284583 |
DrugBank | DB01202 |
UNII ID | 44YRR34555 (ChemIDplus, GSRS) |