Levosalbutamol
Levosalbutamol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target beta-2 adrenergic receptor.
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Commercial
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Clinical
Clinical Trials
936 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 32 | 72 | 126 | 112 | 98 | 437 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 12 | 34 | 84 | 75 | 64 | 267 |
| Obstructive lung diseases | D008173 | — | — | 5 | 26 | 58 | 43 | 38 | 168 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | 5 | 23 | 67 | 41 | 28 | 163 |
| Respiratory aspiration | D053120 | EFO_1001839 | — | 14 | 2 | 15 | 4 | 4 | 39 |
| Healthy volunteers/patients | — | — | — | 19 | 1 | — | 3 | 15 | 38 |
| Bronchiolitis | D001988 | — | — | 3 | 4 | 1 | 5 | 13 | 26 |
| Status asthmaticus | D013224 | — | — | 2 | 5 | 4 | 4 | 6 | 18 |
| Bronchial spasm | D001986 | — | — | — | 2 | 5 | 4 | 3 | 14 |
| Exercise-induced asthma | D001250 | — | J45.990 | — | — | 6 | 4 | 1 | 11 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | 2 | — | 11 | 13 |
| Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | 2 | 4 | 2 | — | 1 | 7 |
| Hypertension | D006973 | EFO_0000537 | I10 | 1 | 2 | 1 | — | 2 | 6 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | 1 | 1 | — | 4 | 5 |
| Respiratory tract diseases | D012140 | — | — | — | 1 | 1 | — | 2 | 4 |
| Respiration disorders | D012120 | — | J00-J99 | — | — | 1 | — | 3 | 4 |
| Acute lung injury | D055371 | EFO_0004610 | — | 1 | 2 | 1 | — | 1 | 4 |
| Bronchial hyperreactivity | D016535 | — | — | — | — | 1 | — | 3 | 4 |
| Transient tachypnea of the newborn | D059245 | — | P22.1 | 2 | — | 2 | — | — | 4 |
| Tachypnea | D059246 | — | R06.82 | 2 | — | 1 | — | — | 3 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cough | D003371 | — | R05 | — | 1 | — | — | 1 | 2 |
| Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | 1 | 1 | — | — | — | 2 |
| Discoid lupus erythematosus | D008179 | — | L93.0 | — | 2 | — | — | — | 2 |
| Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | — | 2 | — | — | — | 2 |
| Sclerosis | D012598 | — | — | — | 1 | — | — | 1 | 2 |
| Lymphangioleiomyomatosis | D018192 | — | J84.81 | 1 | 1 | — | — | — | 1 |
| Viral bronchiolitis | D001990 | — | — | — | 1 | — | — | — | 1 |
| Brain death | D001926 | — | G93.82 | — | 1 | — | — | — | 1 |
| Pulmonary edema | D011654 | EFO_1001134 | J81 | — | 1 | — | — | — | 1 |
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | — | 1 | — | — | — | 1 |
Show 3 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 14 | — | — | — | — | 14 |
| Fibrosis | D005355 | — | — | 1 | — | — | — | 9 | 10 |
| Covid-19 | D000086382 | — | U07.1 | 1 | — | — | — | 4 | 5 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | 1 | — | — | — | 3 | 4 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 2 | — | — | — | 1 | 3 |
| Ciliary motility disorders | D002925 | EFO_0003900 | — | 1 | — | — | — | 2 | 3 |
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | — | — | — | 1 | 2 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 1 | — | — | — | — | 1 |
| Cicatrix | D002921 | — | L90.5 | 1 | — | — | — | — | 1 |
| Idiopathic pulmonary fibrosis | D054990 | — | J84.112 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Smoking | D012907 | EFO_0004318 | — | — | — | — | — | 4 | 4 |
| Airway remodeling | D056151 | — | — | — | — | — | — | 3 | 3 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 3 | 3 |
| Respiratory signs and symptoms | D012818 | — | — | — | — | — | — | 2 | 2 |
| Lung neoplasms | D008175 | — | C34.90 | — | — | — | — | 2 | 2 |
| Muscular dystrophies | D009136 | EFO_0000757 | G71.0 | — | — | — | — | 2 | 2 |
| Child mortality | D046688 | — | — | — | — | — | — | 2 | 2 |
| Noninvasive ventilation | D063087 | — | — | — | — | — | — | 2 | 2 |
| Artificial respiration | D012121 | — | — | — | — | — | — | 1 | 1 |
| Pulmonary atelectasis | D001261 | — | J98.1 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Levosalbutamol |
| INN | levosalbutamol |
| Description | (R)-salbutamol is an albuterol. |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1 |
Identifiers
| PDB | — |
| CAS-ID | 34391-04-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1002 |
| ChEBI ID | 8746 |
| PubChem CID | 123600 |
| DrugBank | DB13139 |
| UNII ID | EDN2NBH5SS (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ADRB2
ADRB2
Organism
Homo sapiens
Gene name
ADRB2
Gene synonyms
ADRB2R, B2AR
NCBI Gene ID
Protein name
beta-2 adrenergic receptor
Protein synonyms
adrenergic, beta-2-, receptor, surface, adrenoceptor beta 2 surface, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, catecholamine receptor
Uniprot ID
Mouse ortholog
Adrb2 (11555)
beta-2 adrenergic receptor (Q8BH38)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Levosalbutamol
+
Levalbuterol
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,436 adverse events reported
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