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Drug ReportsLenzilumab
Lenzilumab
Lenzilumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against granulocyte-macrophage colony-stimulating factor.
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Clinical
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Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Covid-19D000086382—U07.1—12——3
Coronavirus infectionsD018352EFO_0007224B34.2——1——1
PneumoniaD011014EFO_0003106J18——1——1
NeoplasmsD009369—C80——1——1
Virus diseasesD014777—B34——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.9—1———1
ArthritisD001168EFO_0005856M05-M14—1———1
AsthmaD001249EFO_0000270J45—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LymphomaD008223—C85.91————1
B-cell lymphomaD016393——1————1
Myelomonocytic leukemia chronicD015477—C93.11————1
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLenzilumab
INNlenzilumab
Description
Lenzilumab (INN; development code KB003) is a humanized monoclonal antibody (class IgG1 kappa) that targets colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF).
Classification
Antibody
Drug classmonoclonal antibodies
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL3707325
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDIE4X6497XK (ChemIDplus, GSRS)
Target
Agency Approved
CSF2
CSF2
Organism
Homo sapiens
Gene name
CSF2
Gene synonyms
GMCSF
NCBI Gene ID
Protein name
granulocyte-macrophage colony-stimulating factor
Protein synonyms
colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, granulocyte macrophage-colony stimulating factor, molgramostim, Molgramostin, Sargramostim
Uniprot ID
Mouse ortholog
Csf2 (12981)
granulocyte-macrophage colony-stimulating factor (P01587)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 618 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5 adverse events reported
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