Lcz696
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196 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | HP_0001635 | I50 | 4 | 18 | 18 | 42 | 43 | 121 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | 14 | 13 | 6 | 5 | 37 |
| Essential hypertension | D000075222 | — | I10 | — | 5 | 5 | 1 | 1 | 12 |
| Systolic heart failure | D054143 | EFO_1001207 | I50.20 | — | — | 1 | 4 | 4 | 9 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | 1 | 4 | 3 | 1 | 9 |
| Infarction | D007238 | EFO_0009463 | — | — | 1 | 4 | 2 | 1 | 8 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 3 | 1 | 1 | 2 | 6 |
| Left ventricular dysfunction | D018487 | — | — | — | 1 | 2 | 1 | 1 | 5 |
| Hypertrophy | D006984 | EFO_0002460 | — | — | 4 | 1 | 1 | — | 5 |
| Systolic murmurs | D054160 | — | R01.1 | — | 1 | 2 | 1 | 1 | 5 |
Show 36 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ventricular remodeling | D020257 | — | — | — | 2 | 2 | — | 3 | 7 |
| Cardiomyopathies | D009202 | EFO_0000318 | I42 | — | 3 | 2 | — | — | 4 |
| Hypertrophic cardiomyopathy | D002312 | EFO_0000538 | I42.1 | — | 3 | 1 | — | — | 3 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 2 | 1 | — | 1 | 3 |
| Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | 1 | 1 | — | — | 3 |
| Inferior wall myocardial infarction | D056989 | EFO_1000983 | — | — | — | 1 | — | 1 | 2 |
| St elevation myocardial infarction | D000072657 | — | — | — | — | 2 | — | — | 2 |
| Congenital heart defects | D006330 | HP_0001627 | Q24.9 | — | 1 | 1 | — | 1 | 2 |
| Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | — | — | 1 | — | — | 1 |
| Erectile dysfunction | D007172 | EFO_0004234 | F52.21 | — | — | 1 | — | — | 1 |
Show 6 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | 1 | — | — | — | 3 |
| Atrial remodeling | D064752 | — | — | — | 1 | — | — | 1 | 2 |
| Covid-19 | D000086382 | — | — | 1 | 1 | — | — | 1 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 2 | — | — | — | 2 |
| Diastolic heart failure | D054144 | EFO_1000899 | I50.30 | — | 2 | — | — | — | 2 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | — | 2 | — | — | — | 2 |
| Chronic renal insufficiency | D051436 | — | N18 | 2 | 1 | — | — | — | 2 |
| Myositis | D009220 | EFO_0000783 | G72.49 | — | 1 | — | — | — | 1 |
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | 1 | — | — | — | 1 |
| Insulin resistance | D007333 | HP_0000855 | — | — | 1 | — | — | — | 1 |
Show 13 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thyroid neoplasms | D013964 | EFO_0003841 | — | 1 | — | — | — | — | 1 |
| Papillary thyroid cancer | D000077273 | — | — | 1 | — | — | — | — | 1 |
| Thyroid diseases | D013959 | HP_0000820 | E00-E07 | 1 | — | — | — | — | 1 |
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Frailty | D000073496 | — | R53.1 | — | — | — | — | 1 | 1 |
| Hematopoietic stem cell transplantation | D018380 | — | — | — | — | — | — | 1 | 1 |
| Hyperkalemia | D006947 | HP_0002153 | E87.5 | — | — | — | — | 1 | 1 |
| Cardio-renal syndrome | D059347 | — | — | — | — | — | — | 1 | 1 |
| Lymphoma | D008223 | — | C85.9 | — | — | — | — | 1 | 1 |
| Univentricular heart | D000080039 | — | Q20.4 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | — |
| INN | — |
| Description | — |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | — |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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