Landiolol
Landiolol is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | 3 | 1 | 1 | 5 |
| Cardiac surgical procedures | D006348 | — | — | — | — | 1 | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tachycardia | D013610 | HP_0001649 | R00.0 | — | 2 | 1 | — | 1 | 3 |
| Coronary artery disease | D003324 | — | I25.1 | — | 2 | 1 | — | — | 3 |
| Septic shock | D012772 | — | A48.3 | — | — | 1 | — | 1 | 2 |
| Supraventricular tachycardia | D013617 | HP_0004755 | I47.1 | — | 2 | 1 | — | — | 2 |
| Postoperative complications | D011183 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | 1 | — | — | — | 2 |
| Coronary disease | D003327 | — | — | — | 2 | — | — | — | 2 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | 2 | — | — | — | 2 |
| Pharmacokinetics | D010599 | — | — | — | 1 | — | — | — | 1 |
| Heart arrest | D006323 | EFO_0009492 | I46 | 1 | 1 | — | — | — | 1 |
| Out-of-hospital cardiac arrest | D058687 | — | — | 1 | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Shock | D012769 | — | R57.1 | — | — | — | — | 1 | 1 |
| Heart failure | D006333 | HP_0001635 | I50 | — | — | — | — | 1 | 1 |
| Left ventricular dysfunction | D018487 | — | — | — | — | — | — | 1 | 1 |
| Ventricular dysfunction | D018754 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Landiolol |
| INN | landiolol |
| Description | Landiolol is a member of morpholines. |
| Classification | Small molecule |
| Drug class | beta-blockers (propranolol type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)OC[C@@H](COC(=O)CCc2ccc(OC[C@@H](O)CNCCNC(=O)N3CCOCC3)cc2)O1 |
Identifiers
| PDB | — |
| CAS-ID | 133242-30-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1742466 |
| ChEBI ID | — |
| PubChem CID | 114905 |
| DrugBank | — |
| UNII ID | 62NWQ924LH (ChemIDplus, GSRS) |
Target
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Trends
PubMed Central
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Additional graphs summarizing 741 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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67 adverse events reported
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