Landiolol
Rapiblyk (landiolol) is a small molecule pharmaceutical. Landiolol was first approved as Rapiblyk on 2024-11-22.
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Events Timeline
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Rapiblyk
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Landiolol hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| RAPIBLYK | AOP Health | N-217202 RX | 2024-11-22 | 1 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| rapiblyk | New Drug Application | 2025-04-29 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| atrial fibrillation | EFO_0000275 | D001281 | I48.0 |
| atrial flutter | EFO_0003911 | D001282 | — |
| supraventricular tachycardia | — | D013617 | I47.1 |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
17 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | 1 | — | — | — | 2 |
| Pharmacokinetics | D010599 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Landiolol |
| INN | landiolol |
| Description | Landiolol is a member of morpholines. |
| Classification | Small molecule |
| Drug class | beta-blockers (propranolol type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)OC[C@@H](COC(=O)CCc2ccc(OC[C@@H](O)CNCCNC(=O)N3CCOCC3)cc2)O1 |
Identifiers
| PDB | — |
| CAS-ID | 133242-30-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1742466 |
| ChEBI ID | — |
| PubChem CID | 114905 |
| DrugBank | — |
| UNII ID | 62NWQ924LH (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 861 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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76 adverse events reported
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