Expiration | Code | ||
---|---|---|---|
lanadelumab, Takhzyro, Takeda Pharmaceuticals U.S.A., Inc. | |||
2030-02-03 | Orphan excl. |
Code | Description |
---|---|
J0593 | Injection, lanadelumab-flyo, 1 mg (code may be used for medicare when drug administered under direct supervision of a physician, not for use when drug is self-administered) |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hereditary angioedemas | D054179 | EFO_0004131 | — | 2 | — | 6 | — | 6 | 14 |
Angioedema | D000799 | EFO_0005532 | T78.3 | — | — | 2 | — | 2 | 4 |
Covid-19 | D000086382 | — | U07.1 | 1 | 1 | 1 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hereditary autoinflammatory diseases | D056660 | — | — | — | 1 | — | — | — | 1 |
Hypotension | D007022 | EFO_0005251 | I95 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | — | — | — | — | 3 |
Pneumonia | D011014 | EFO_0003106 | — | 1 | — | — | — | — | 1 |
Lung injury | D055370 | — | S27.30 | 1 | — | — | — | — | 1 |
Drug common name | Lanadelumab |
INN | lanadelumab |
Description | Lanadelumab, sold under the brand name Takhzyro, is a human monoclonal antibody (class IgG1 kappa) that targets plasma kallikrein (pKal) in order to promote prevention of angioedema in people with hereditary angioedema. Lanadelumab, was approved in the United States as the first monoclonal antibody indicated for prophylactic treatment to prevent hereditary angioedema attacks. Lanadelumab is the first treatment for hereditary angioedema prevention made by using cells within a lab, not human plasma.
|
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL3545189 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB14597 |
UNII ID | 2372V1TKXK (ChemIDplus, GSRS) |