PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
AboutPricing
Drug ReportsLampalizumab
Lampalizumab
Lampalizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against complement factor D.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
No data
Clinical
Clinical Trials
208 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938—C952532212170
Myeloid leukemia acuteD015470—C92.0212571146
Myeloid leukemiaD007951—C92212371144
Myelodysplastic syndromesD009190—D46131311—23
SyndromeD013577——101121120
Myelomonocytic leukemia chronicD015477—C93.152—1—7
Myelomonocytic leukemia juvenileD054429—C93.352—1—7
ArthritisD001168HP_0001369M05-M14—311—5
DyspepsiaD004415EFO_0008533K30—1—135
Rheumatoid arthritisD001172EFO_0000685M06.9—3—1—4
Show 26 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Precursor cell lymphoblastic leukemia-lymphomaD054198——81615——37
Lymphoid leukemiaD007945—C9161013——27
LymphomaD008223—C85.95147——24
NeoplasmsD009369—C80871—116
CarcinomaD002277—C80.0562——12
Non-hodgkin lymphomaD008228—C85.9454——12
Myeloproliferative disordersD009196—D47.1621——8
Hodgkin diseaseD006689—C81241——7
Philadelphia chromosomeD010677——133——7
Non-small-cell lung carcinomaD002289——342——7
Show 55 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
RecurrenceD012008——1014———21
PreleukemiaD011289——109———15
Multiple myelomaD009101—C90.033———6
Hematologic neoplasmsD019337——24———5
Follicular lymphomaD008224—C8224———5
Mantle-cell lymphomaD020522——15———5
Biphenotypic leukemia acuteD015456—C95.034———5
T-cell lymphomaD016399———5———5
Neoplasm metastasisD009362EFO_0009708—31———4
Ovarian neoplasmsD010051EFO_0003893C5622———4
Show 87 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———7————7
Pancreatic neoplasmsD010190EFO_0003860C252————2
Myelodysplastic-myeloproliferative diseasesD054437——2————2
Leukemia myeloid chronic atypical bcr-abl negativeD054438—C92.21————1
ThrombocytosisD013922HP_0001894D75.831————1
Skin neoplasmsD012878EFO_0004198C441————1
Cutaneous malignant melanomaD000096142——1————1
Myeloid sarcomaD023981—C92.31————1
HivD006678——1————1
Medication adherenceD055118EFO_0006344—1————1
Show 2 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Gastrointestinal diseasesD005767——————22
Cardiovascular diseasesD002318HP_0001626—————11
Gastrointestinal stromal tumorsD046152EFO_0000505C49.A————11
PouchitisD019449EFO_0003921K91.850————11
Esophageal neoplasmsD004938—C15————11
Hepatitis bD006509——————11
Chronic hepatitis bD019694EFO_0004239B18.1————11
HepatitisD006505HP_0012115K75.9————11
Chronic hepatitisD006521—K73.9————11
Hepatitis aD006506EFO_0007305B15————11
Show 20 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameLampalizumab
INNlampalizumab
Description
Lampalizumab (humanized mab)
Classification
Antibody
Drug classionotropic non-NMDA (N-methyl D-aspartate) glutamate receptors [AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) and/or KA (kainite antagonist) receptors]; monoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL2109408
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDUWU93Y99R3 (ChemIDplus, GSRS)
Target
Agency Approved
CFD
CFD
Organism
Homo sapiens
Gene name
CFD
Gene synonyms
DF, PFD
NCBI Gene ID
Protein name
complement factor D
Protein synonyms
Adipsin, C3 convertase activator, complement factor D preproprotein, D component of complement (adipsin), Properdin factor D
Uniprot ID
Mouse ortholog
Cfd (11537)
complement factor D (P03953)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 329 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use