Lampalizumab
Lampalizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against complement factor D.
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Commercial
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Clinical
Clinical Trials
106 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Geographic atrophy | D057092 | — | — | 1 | 3 | — | — | — | 4 |
| Atrophy | D001284 | — | — | 1 | 3 | — | — | — | 4 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | — | — | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
| Sarcoma | D012509 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Lampalizumab |
| INN | lampalizumab |
| Description | Lampalizumab (humanized mab) |
| Classification | Antibody |
| Drug class | ionotropic non-NMDA (N-methyl D-aspartate) glutamate receptors [AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) and/or KA (kainite antagonist) receptors]; monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109408 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | UWU93Y99R3 (ChemIDplus, GSRS) |
Target
Agency Approved
CFD
CFD
Alternate
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Variants
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Trends
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Safety
Black-box Warning
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Adverse Events
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