Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
signs and symptoms pathological conditions | D013568 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TRANDATE HCT | GSK | N-019174 DISCN | 1987-04-10 | 4 products |
NORMOZIDE | Merck & Co | N-019046 DISCN | 1987-04-06 | 4 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
LABETALOL HYDROCHLORIDE IN DEXTROSE | Hikma Pharmaceuticals | N-213330 RX | 2020-11-09 | 1 products, RLD, RS |
LABETALOL HYDROCHLORIDE IN SODIUM CHLORIDE | Hikma Pharmaceuticals | N-213330 RX | 2020-11-09 | 3 products, RLD, RS |
LABETALOL HYDROCHLORIDE | Hikma Pharmaceuticals | N-213330 RX | 2024-08-19 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
labetalol | ANDA | 2018-04-06 |
labetalol hcl | ANDA | 2024-10-07 |
labetalol hcl in dextrose labetalol hcl in sodium chloride | New Drug Application | 2022-03-01 |
labetalol hcl in dextrose labetalol hcl in sodium chloride labetalol hydrochloride | New Drug Application | 2024-09-20 |
labetalol hydrochloride | ANDA | 2025-03-20 |
trandate | New Drug Application | 2009-12-14 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 1 | 1 |
Drug common name | Labetalol |
INN | labetalol |
Description | Labetalol is a diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure. It has a role as an antihypertensive agent, a sympatholytic agent, an alpha-adrenergic antagonist and a beta-adrenergic antagonist. It contains a (R,R)-labetalol, a (S,S)-labetalol, a (R,S)-labetolol and a (S,R)-labetolol. |
Classification | Small molecule |
Drug class | combined alpha and beta blockers |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC(CCc1ccccc1)NCC(O)c1ccc(O)c(C(N)=O)c1 |
PDB | — |
CAS-ID | 36894-69-6 |
RxCUI | — |
ChEMBL ID | CHEMBL429 |
ChEBI ID | 6343 |
PubChem CID | 3869 |
DrugBank | DB00598 |
UNII ID | R5H8897N95 (ChemIDplus, GSRS) |