LOMIBUVIR
Lomibuvir is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Commercial
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis c | D006526 | — | B19.2 | 2 | 4 | — | — | — | 5 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 1 | 4 | — | — | — | 4 |
| Hepatitis | D006505 | — | K75.9 | 1 | 4 | — | — | — | 4 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | 1 | 4 | — | — | — | 4 |
| Chronic hepatitis | D006521 | — | K73.9 | — | 3 | — | — | — | 3 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | — | 1 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | — | 1 | — | — | — | 1 |
| Virus diseases | D014777 | — | B34 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | LOMIBUVIR |
| INN | lomibuvir |
| Description | 5-(3,3-dimethylbut-1-ynyl)-3-[(4-hydroxycyclohexyl)-[(4-methylcyclohexyl)-oxomethyl]amino]-2-thiophenecarboxylic acid is a thiophenecarboxylic acid. |
| Classification | Small molecule |
| Drug class | antivirals: RNA polymerase (NS5B) inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)(C)C#Cc1cc(N(C(=O)[C@H]2CC[C@H](C)CC2)[C@H]2CC[C@H](O)CC2)c(C(=O)O)s1 |
Identifiers
| PDB | — |
| CAS-ID | 1026785-55-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3039503 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 37L2LF4A2D (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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22 adverse events reported
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