Ketotifen
Alaway, Ketotifen, Zaditor (ketotifen) is a small molecule pharmaceutical. Ketotifen was first approved as Ketotifen fumarate on 2006-05-09. It is used to treat allergic conjunctivitis in the USA. The pharmaceutical is active against histamine H1 receptor.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| eye diseases | D005128 |
| immune system diseases | D007154 |
Trade Name
FDA
EMA
Alaway, Ketotifen, Zaditor (discontinued: Acuvue theravision with ketotifen, Alaway, Zaditor)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ketotifen fumarate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ALAWAY | Bausch Health Companies | N-021996 OTC | 2006-12-01 | 1 products, RLD, RS |
| CHILDREN'S ALAWAY | Bausch Health Companies | N-021996 OTC | 2015-02-11 | 1 products, RLD |
Show 2 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| acuvue theravision with ketotifen | New Drug Application | 2022-03-11 |
| alaway | New Drug Application | 2022-05-01 |
| allergy eye drops | ANDA | 2022-01-25 |
| equate eye itch relief | New Drug Application | 2021-03-23 |
| eye itch | ANDA | 2022-02-10 |
| eye itch releif | New Drug Application | 2024-07-22 |
| eye itch relief | New Drug Application | 2024-10-01 |
| good neighbor pharmacy eye itch relief | ANDA | 2013-07-18 |
| itchy eye | ANDA | 2022-02-11 |
| ketotifen fumarate | ANDA | 2024-07-12 |
Show 3 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| allergic conjunctivitis | EFO_0007141 | D003233 | H10.44 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
KETOTIFEN FUMARATE, ACUVUE THERAVISION WITH KETOTIFEN, JOHNSON JOHNSON VISN | |||
| 2025-02-25 | NP | ||
ATC Codes
R: Respiratory system drugs
— R06: Antihistamines for systemic use
— R06A: Antihistamines for systemic use
— R06AX: Other antihistamines for systemic use in atc
— R06AX17: Ketotifen
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01G: Decongestants and antiallergics
— S01GX: Other antiallergics in atc
— S01GX08: Ketotifen
HCPCS
No data
Clinical
Clinical Trials
38 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Conjunctivitis | D003231 | HP_0000509 | H10 | 1 | — | — | 1 | — | 2 |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | 1 | — | — | 1 | — | 2 |
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Ketotifen |
| INN | ketotifen |
| Description | Ketotifen is an organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect. It has a role as a H1-receptor antagonist and an anti-asthmatic drug. It is an organosulfur heterocyclic compound, an organic heterotricyclic compound, a cyclic ketone, a member of piperidines, an olefinic compound and a tertiary amino compound. It is a conjugate base of a ketotifen(1+). |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CN1CCC(=C2c3ccccc3CC(=O)c3sccc32)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 34580-13-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL534 |
| ChEBI ID | — |
| PubChem CID | 3827 |
| DrugBank | DB00920 |
| UNII ID | X49220T18G (ChemIDplus, GSRS) |
Target
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Ketotifen
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 2,591 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
5,799 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use