Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NIZORAL ANTI-DANDRUFF | Kramer Laboratories | N-020310 OTC | 1997-10-10 | 1 products, RLD, RS |
EXTINA | Mylan | N-021738 RX | 2007-06-12 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
hydrocortisone 2.5% / iodoquinol 1% / ketoconazole 2% | unapproved drug other | 2019-05-16 |
hydrocortisone 2.5% / ketoconazole 2% | unapproved drug other | 2019-05-16 |
nizoral scalp itch relief | C200263 | 2024-01-05 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 19 | 3 | — | 2 | — | 24 |
Seborrheic dermatitis | D012628 | HP_0001051 | L21 | — | 2 | 1 | 1 | 1 | 5 |
Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | 1 | 1 | 1 | — | 3 |
Hiv infections | D015658 | EFO_0000764 | B20 | 1 | — | — | 1 | 1 | 3 |
Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | — | — | 1 | — | 3 |
Thromboembolism | D013923 | HP_0001907 | — | — | 1 | — | 1 | — | 2 |
Tinea versicolor | D014010 | EFO_0007439 | B36.0 | — | — | — | 2 | — | 2 |
Kidney transplantation | D016030 | — | — | — | — | — | 1 | — | 1 |
Intellectual disability | D008607 | EFO_0003847 | F73 | — | — | — | 1 | — | 1 |
Tardive dyskinesia | D000071057 | — | G24.01 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Prostatic neoplasms | D011471 | — | C61 | 3 | 18 | 5 | — | 4 | 28 |
Tinea pedis | D014008 | EFO_0007512 | B35.3 | — | 1 | 5 | — | — | 6 |
Bacterial vaginosis | D016585 | EFO_0003932 | — | — | — | 2 | — | — | 2 |
Candidiasis | D002177 | — | B37 | — | — | 1 | — | 1 | 2 |
Pituitary acth hypersecretion | D047748 | EFO_1001110 | E24.0 | — | — | 1 | — | 1 | 2 |
Cushing syndrome | D003480 | EFO_0003099 | E24 | — | — | 1 | — | 1 | 2 |
Cerebral hemorrhage | D002543 | — | — | — | — | 1 | — | — | 1 |
Vulvovaginal candidiasis | D002181 | EFO_0007543 | B37.3 | — | — | 1 | — | — | 1 |
Tinea | D014005 | EFO_0007510 | B35.4 | — | — | 1 | — | — | 1 |
Burns | D002056 | — | T30.0 | — | 1 | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 3 | 2 | — | — | — | 4 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 1 | — | — | — | 3 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 1 | — | — | — | 1 |
Castration-resistant prostatic neoplasms | D064129 | — | — | — | 1 | — | — | — | 1 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 1 | — | — | — | 1 |
Psoriasis | D011565 | EFO_0000676 | L40 | — | 1 | — | — | — | 1 |
Adenocarcinoma | D000230 | — | — | 1 | 1 | — | — | — | 1 |
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | 1 | — | — | — | 1 |
Hip fractures | D006620 | EFO_0003964 | S72.00 | — | 1 | — | — | — | 1 |
Femur head necrosis | D005271 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 49 | — | — | — | 1 | 50 |
Pharmacokinetics | D010599 | — | — | 6 | — | — | — | — | 6 |
Drug interactions | D004347 | — | — | 3 | — | — | — | — | 3 |
Lymphoma | D008223 | — | C85.9 | 3 | — | — | — | — | 3 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 3 | — | — | — | — | 3 |
Neuroblastoma | D009447 | EFO_0000621 | — | 2 | — | — | — | 1 | 3 |
Hepatitis c | D006526 | — | B19.2 | 2 | — | — | — | — | 2 |
Hypogonadism | D007006 | HP_0000044 | E23.0 | 1 | — | — | — | 1 | 2 |
Glioma | D005910 | EFO_0000520 | — | 2 | — | — | — | — | 2 |
Osteoporosis | D010024 | HP_0000939 | M81.0 | 2 | — | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Delirium | D003693 | — | R41.0 | — | — | — | — | 1 | 1 |
Gonadal disorders | D006058 | — | — | — | — | — | — | 1 | 1 |
Kallmann syndrome | D017436 | Orphanet_478 | E23.0 | — | — | — | — | 1 | 1 |
Dermatitis | D003872 | HP_0011123 | L30.9 | — | — | — | — | 1 | 1 |
Tinea capitis | D014006 | — | B35.0 | — | — | — | — | 1 | 1 |
Drug common name | Ketoconazole |
INN | ketoconazole |
Description | 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine is a dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively. It is an ether, a member of imidazoles, a N-arylpiperazine, a dioxolane, a dichlorobenzene and a N-acylpiperazine. |
Classification | Small molecule |
Drug class | systemic antifungals (miconazole type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(=O)N1CCN(c2ccc(OCC3COC(Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 |
PDB | — |
CAS-ID | 65277-42-1 |
RxCUI | — |
ChEMBL ID | CHEMBL157101 |
ChEBI ID | 48339 |
PubChem CID | 3823 |
DrugBank | DB01026 |
UNII ID | R9400W927I (ChemIDplus, GSRS) |