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Drug ReportsItolizumab
Itolizumab
Itolizumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against T-cell differentiation antigen CD6.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Graft vs host diseaseD006086D89.812113
Covid-19D000086382112
CoronavirusD01793411
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Respiratory distress syndromeD012128EFO_1000637J80112
Acute lung injuryD055371EFO_0004610112
Newborn respiratory distress syndromeD012127P22112
SyndromeD013577112
Cytokine release syndromeD000080424D89.8311
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lupus nephritisD008181EFO_000576111
Systemic lupus erythematosusD008180HP_0002725M3211
NephritisD009393N0511
AsthmaD001249EFO_0000270J4511
DermatomyositisD003882EFO_0000398M3311
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameItolizumab
INNitolizumab
Description
Itolizumab (humanized mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID
RxCUI
ChEMBL IDCHEMBL1743033
ChEBI ID
PubChem CID
DrugBank
UNII IDXQQ2RHV14N (ChemIDplus, GSRS)
Target
Agency Approved
CD6
CD6
Organism
Homo sapiens
Gene name
CD6
Gene synonyms
NCBI Gene ID
Protein name
T-cell differentiation antigen CD6
Protein synonyms
CD6, CD6 antigen, T12, TP120
Uniprot ID
Mouse ortholog
Cd6 (12511)
T-cell differentiation antigen CD6 (Q61003)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 333 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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7 adverse events reported
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