Ioxaglic acid
Hexabrix (ioxaglic acid) is a small molecule pharmaceutical. Ioxaglic acid was first approved as Hexabrix on 1985-07-26.
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Clinical
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5 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Renal insufficiency | D051437 | HP_0000083 | N19 | — | — | 1 | 1 | 1 | 3 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | 1 | — | 1 | 2 |
| Acute kidney injury | D058186 | HP_0001919 | N17 | — | — | 1 | — | 1 | 2 |
Indications Phases 2
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | — | — | — | — | 1 | 1 |
| Salivary gland diseases | D012466 | EFO_0008581 | K11 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ioxaglic acid |
| INN | ioxaglic acid |
| Description | Ioxaglic acid is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position. It has a role as a radioopaque medium. It is an organoiodine compound, a benzenedicarboxamide and a member of benzoic acids. |
| Classification | Small molecule |
| Drug class | iodine-containing contrast media |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CNC(=O)c1c(I)c(C(=O)NCC(=O)Nc2c(I)c(C(=O)O)c(I)c(C(=O)NCCO)c2I)c(I)c(N(C)C(C)=O)c1I |
Identifiers
| PDB | — |
| CAS-ID | 59017-64-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201291 |
| ChEBI ID | 31718 |
| PubChem CID | 3742 |
| DrugBank | DB09313 |
| UNII ID | Z40X7EI2AF (ChemIDplus, GSRS) |
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Safety
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301 adverse events reported
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