Iomeprol
Iomervu (iomeprol) is a small molecule pharmaceutical. Iomeprol was first approved as Iomervu on 2024-11-27.
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FDA approval date
EMA approval date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Iomervu
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Iomeprol
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| IOMERVU | Bracco Diagnostics | N-216016 RX | 2024-11-27 | 13 products, RLD, RS |
| IOMERVU | Bracco Diagnostics | N-216017 RX | 2024-11-27 | 13 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| iomeron | unapproved drug for use in drug shortage | 2024-12-06 |
Indications
FDA
EMA
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Agency Specific
FDA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
17 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Renal insufficiency | D051437 | HP_0000083 | N19 | — | — | — | 1 | 1 | 2 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | — | 2 | — | 2 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | 2 | — | 2 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | — | 1 | — | 1 |
| Arteriosclerosis | D001161 | EFO_0009086 | I70 | — | — | — | 1 | — | 1 |
| Balloon angioplasty coronary | D015906 | EFO_0003951 | — | — | — | — | 1 | — | 1 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | — | — | 1 | — | 1 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | — | — | — | 1 | — | 1 |
| Aortic diseases | D001018 | — | — | — | — | — | 1 | — | 1 |
| Caroli disease | D016767 | EFO_1001286 | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carotid artery diseases | D002340 | EFO_0003781 | — | — | 1 | 1 | — | — | 1 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | 1 | 1 | — | — | 1 |
| Atherosclerotic plaque | D058226 | HP_0031678 | I70 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gallstones | D042882 | EFO_0004210 | — | — | — | — | — | 2 | 2 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | — | — | 1 | 1 |
| Infarction | D007238 | EFO_0009463 | — | — | — | — | — | 1 | 1 |
| Neoplasms | D009369 | — | C80 | — | — | — | — | 1 | 1 |
| Soft tissue neoplasms | D012983 | — | — | — | — | — | — | 1 | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | — | — | — | 1 | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | — | — | 1 | 1 |
| Four-dimensional computed tomography | D056973 | — | — | — | — | — | — | 1 | 1 |
| Diagnostic imaging | D003952 | — | — | — | — | — | — | 1 | 1 |
| Acute cholecystitis | D041881 | EFO_1001289 | K81.0 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Iomeprol |
| INN | iomeprol |
| Description | Iomeprol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is a benzenedicarboxamide and an organoiodine compound. |
| Classification | Small molecule |
| Drug class | iodine-containing contrast media |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CN(C(=O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I |
Identifiers
| PDB | — |
| CAS-ID | 78649-41-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107214 |
| ChEBI ID | 31710 |
| PubChem CID | 3731 |
| DrugBank | DB11705 |
| UNII ID | 17E17JBP8L (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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887 adverse events reported
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