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Drug ReportsInosine
Inosine
Inosine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target P2Y purinoceptor 4.
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Variants
Financial
Trends
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Events Timeline
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2Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
rejuvesolNew Drug Application2023-02-14
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
D06: Antibiotics and chemotherapeutics for dermatological use
D06B: Chemotherapeutics for topical use
D06BB: Antivirals, topical
D06BB05: Inosine
G: Genito urinary system and sex hormones
G01: Gynecological antiinfectives and antiseptics
G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
G01AX: Other gynecological antiinfectives and antiseptics in atc
G01AX02: Inosine
J: Antiinfectives for systemic use
J05: Antivirals for systemic use
J05A: Direct acting antivirals
J05AX: Other antivirals in atc
J05AX05: Inosine pranobex
S: Sensory organ drugs
S01: Ophthalmologicals
S01X: Other ophthalmologicals in atc
S01XA: Other ophthalmologicals in atc
S01XA10: Inosine
HCPCS
No data
Clinical
Clinical Trials
224 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B20213
Acquired immunodeficiency syndromeD000163EFO_0000765B20213
Progressive multifocal leukoencephalopathyD007968EFO_0007455A81.211
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Aids-related complexD000386EFO_0007137B2022
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameInosine
INNinosine
Description
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. It was discovered in 1965 in analysis of RNA transferase. Inosine is commonly found in tRNAs and is essential for proper translation of the genetic code in wobble base pairs.
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=c1[nH]cnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Identifiers
PDB
CAS-ID58-63-9
RxCUI
ChEMBL IDCHEMBL1556
ChEBI ID17596
PubChem CID6021
DrugBankDB04335
UNII ID5A614L51CT (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
P2RY4
P2RY4
Organism
Homo sapiens
Gene name
P2RY4
Gene synonyms
NRU
NCBI Gene ID
Protein name
P2Y purinoceptor 4
Protein synonyms
P2P, pyrimidinergic receptor P2Y, G-protein coupled, 4, UNR, Uridine nucleotide receptor
Uniprot ID
Mouse ortholog
P2ry4 (57385)
P2Y purinoceptor 4 (Q9JJS7)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 31,545 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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84 adverse events reported
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