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Drug ReportsInosine
Inosine
Inosine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target P2Y purinoceptor 4.
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Events Timeline
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2Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
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Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
rejuvesolNew Drug Application2023-02-14
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06B: Chemotherapeutics for topical use
— D06BB: Antivirals, topical
— D06BB05: Inosine
G: Genito urinary system and sex hormones
— G01: Gynecological antiinfectives and antiseptics
— G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
— G01AX: Other gynecological antiinfectives and antiseptics in atc
— G01AX02: Inosine
J: Antiinfectives for systemic use
— J05: Antivirals for systemic use
— J05A: Direct acting antivirals
— J05AX: Other antivirals in atc
— J05AX05: Inosine pranobex
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01X: Other ophthalmologicals in atc
— S01XA: Other ophthalmologicals in atc
— S01XA10: Inosine
HCPCS
No data
Clinical
Clinical Trials
225 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hematologic diseasesD006402EFO_0005803D75.9——1——1
Thrombocytopenic purpura idiopathicD016553EFO_0007160D69.3——1——1
ThrombocytopeniaD013921HP_0001873D69.6——1——1
Hemostatic disordersD020141————1——1
Thrombocytopenic purpuraD011696————1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameInosine
INNinosine
Description
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. It was discovered in 1965 in analysis of RNA transferase. Inosine is commonly found in tRNAs and is essential for proper translation of the genetic code in wobble base pairs.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
O=c1[nH]cnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Identifiers
PDB—
CAS-ID58-63-9
RxCUI—
ChEMBL IDCHEMBL1556
ChEBI ID17596
PubChem CID6021
DrugBankDB04335
UNII ID5A614L51CT (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
P2RY4
P2RY4
Organism
Homo sapiens
Gene name
P2RY4
Gene synonyms
NRU
NCBI Gene ID
5030
Protein name
P2Y purinoceptor 4
Protein synonyms
P2P, pyrimidinergic receptor P2Y, G-protein coupled, 4, UNR, Uridine nucleotide receptor
Uniprot ID
Q5JT22
Mouse ortholog
P2ry4 (57385)
P2Y purinoceptor 4 (Q9JJS7)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 31,706 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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86 adverse events reported
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