Tradename | Proper name | Company | Number | Date | Products |
---|---|---|---|---|---|
Remicade | infliximab | Johnson & Johnson | N-103772 RX | 1998-08-24 | 1 products |
Expiration | Code | ||
---|---|---|---|
infliximab, Remicade, Janssen Biotech, Inc. | |||
2118-09-23 | Orphan excl. |
Code | Description |
---|---|
EJ | Subsequent claims for a defined course of therapy, e.g., epo, sodium hyaluronate, infliximab |
J1745 | Injection, infliximab, excludes biosimilar, 10 mg |
Q5103 | Injection, infliximab-dyyb, biosimilar, (inflectra), 10 mg |
Q5104 | Injection, infliximab-abda, biosimilar, (renflexis), 10 mg |
Q5109 | Injection, infliximab-qbtx, biosimilar, (ixifi), 10 mg |
Q5121 | Injection, infliximab-axxq, biosimilar, (avsola), 10 mg |
S9359 | Home infusion therapy, anti-tumor necrosis factor intravenous therapy; (e.g., infliximab); administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Crohn disease | D003424 | EFO_0000384 | K50 | 2 | 7 | 29 | 34 | 78 | 146 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 2 | 4 | 29 | 29 | 56 | 120 |
Ulcerative colitis | D003093 | EFO_0000729 | K51 | 3 | 3 | 11 | 22 | 53 | 91 |
Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 2 | 3 | 3 | 11 | 55 | 73 |
Psoriasis | D011565 | EFO_0000676 | L40 | — | 2 | 11 | 7 | 21 | 41 |
Ankylosing spondylitis | D013167 | EFO_0003898 | M45 | 3 | — | 5 | 11 | 22 | 41 |
Psoriatic arthritis | D015535 | EFO_0003778 | L40.5 | — | — | 4 | 5 | 15 | 24 |
Covid-19 | D000086382 | — | U07.1 | — | 2 | 2 | 2 | 2 | 8 |
Spondylarthritis | D025241 | — | — | — | — | — | 2 | 5 | 7 |
Graft vs host disease | D006086 | — | D89.81 | 1 | 3 | 1 | 1 | — | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Mucocutaneous lymph node syndrome | D009080 | EFO_0004246 | M30.3 | 1 | 1 | 6 | — | — | 8 |
Colitis | D003092 | EFO_0003872 | K52.9 | 2 | 4 | 1 | — | 1 | 6 |
Juvenile arthritis | D001171 | EFO_1002007 | M08 | — | 1 | 2 | — | 2 | 5 |
Fatigue | D005221 | HP_0012378 | R53.83 | — | 1 | 1 | — | 2 | 4 |
Behcet syndrome | D001528 | EFO_0003780 | M35.2 | 1 | 1 | 3 | — | — | 4 |
Sarcoidosis | D012507 | EFO_0000690 | D80-D89 | — | — | 2 | — | 2 | 4 |
Vasculitis | D014657 | HP_0002633 | — | 1 | 2 | 1 | — | — | 3 |
Lung neoplasms | D008175 | HP_0100526 | C34.90 | 1 | 2 | 1 | — | — | 3 |
Cachexia | D002100 | HP_0004326 | R64 | — | 2 | 1 | — | — | 3 |
Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | 1 | 1 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Melanoma | D008545 | — | — | 2 | 4 | — | — | 1 | 6 |
Takayasu arteritis | D013625 | EFO_1001857 | M31.4 | — | 3 | — | — | 1 | 4 |
Stevens-johnson syndrome | D013262 | EFO_0004276 | L51.1 | 2 | 3 | — | — | — | 3 |
Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | 1 | — | — | — | 2 |
Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | 1 | — | — | 1 | 2 |
Non-small-cell lung carcinoma | D002289 | — | — | 2 | 2 | — | — | — | 2 |
Reperfusion injury | D015427 | — | — | 1 | 1 | — | — | — | 2 |
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | 1 | — | — | 1 | 2 |
Inflammation | D007249 | MP_0001845 | — | 1 | 2 | — | — | — | 2 |
Hidradenitis suppurativa | D017497 | — | L73.2 | 1 | 1 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | — | — | — | — | 3 |
Scleritis | D015423 | HP_0100534 | H15.0 | 1 | — | — | — | 1 | 2 |
Energy metabolism | D004734 | — | — | 1 | — | — | — | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Rheumatic diseases | D012216 | — | M79.0 | — | — | — | — | 2 | 2 |
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | — | — | 2 | 2 |
Intestinal diseases | D007410 | HP_0002242 | K63.9 | — | — | — | — | 2 | 2 |
Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
Brain diseases | D001927 | HP_0001298 | G93.40 | — | — | — | — | 1 | 1 |
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | — | — | — | — | 1 | 1 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | — | — | 1 | 1 |
Dementia | D003704 | EFO_0003862 | F03 | — | — | — | — | 1 | 1 |
Infections | D007239 | EFO_0000544 | — | — | — | — | — | 1 | 1 |
Lactation | D007774 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Infliximab |
INN | infliximab |
Description | Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, and Behçet's disease. It is given by slow injection into a vein, typically at six- to eight-week intervals.
|
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | >6UGS:H,A|Infliximab (Remicade) Fab Heavy Chain
EVKLEESGGGLVQPGGSMKLSCVASGFIFSNHWMNWVRQSPEKGLEWVAEIRSKSINSATHYAESVKGRFTISRDDSKSA
VYLQMTDLRTEDTGVYYCSRNYYGSTYDYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVS
WNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKT
>6UGS:L,B|Infliximab (Remicade) Fab Light Chain
DILLTQSPAILSVSPGERVSFSCRASQFVGSSIHWYQQRTNGSPRLLIKYASESMSGIPSRFSGSGSGTDFTLSINTVES
EDIADYYCQQSHSWPFTFGSGTNLEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |