Tradename | Company | Number | Date | Products |
---|---|---|---|---|
INDOMETHACIN | Chartwell Pharmaceuticals | N-018829 RX | 1984-08-06 | 2 products |
INDOMETHACIN | Fresenius Kabi | N-022536 RX | 2010-03-17 | 1 products, RLD, RS |
INDOCIN | Zyla Life Sciences | N-018332 RX | 1985-10-10 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
indocin | New Drug Application | 2024-12-16 |
indocin sr | ANDA | 2010-01-12 |
indomethacin | ANDA | 2025-09-26 |
indomethacin er | ANDA | 2010-04-16 |
indomethacin extended-release | ANDA | 2017-12-20 |
tivorbex | New Drug Application | 2018-01-31 |
Expiration | Code | ||
---|---|---|---|
INDOMETHACIN, INDOMETHACIN, ZYDUS | |||
2024-01-30 | CGT |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cataract | D002386 | EFO_0001059 | H26.9 | — | — | — | 2 | — | 2 |
Pain | D010146 | EFO_0003843 | R52 | — | — | 1 | 1 | — | 2 |
Inflammation | D007249 | MP_0001845 | — | — | — | 1 | 1 | — | 2 |
Myopia | D009216 | EFO_0003927 | H52.1 | — | — | — | 1 | — | 1 |
Hyperopia | D006956 | EFO_0006310 | H52.0 | — | — | — | 1 | — | 1 |
Corneal opacity | D003318 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | — | 1 | — | — | 1 |
Allergic rhinitis seasonal | D006255 | EFO_0003956 | J30 | — | — | 1 | — | — | 1 |
Cataract extraction | D002387 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Macular edema | D008269 | — | — | — | 1 | — | — | — | 1 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Diabetic retinopathy | D003930 | EFO_0003770 | — | 1 | — | — | — | — | 1 |
Drug common name | Indomethacin |
INN | indometacin |
Description | Indometacin is a member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It has a role as an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an analgesic, a gout suppressant, a drug metabolite, a xenobiotic metabolite, a xenobiotic, an environmental contaminant and a non-steroidal anti-inflammatory drug. It is a N-acylindole, a member of monochlorobenzenes, an aromatic ether and a member of indole-3-acetic acids. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 |
PDB | — |
CAS-ID | 53-86-1 |
RxCUI | — |
ChEMBL ID | CHEMBL6 |
ChEBI ID | 49662 |
PubChem CID | 3715 |
DrugBank | DB00328 |
UNII ID | XXE1CET956 (ChemIDplus, GSRS) |