
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| INDOMETHACIN | Chartwell Pharmaceuticals | N-018829 RX | 1984-08-06 | 2 products |
| INDOMETHACIN | Fresenius Kabi | N-022536 RX | 2010-03-17 | 1 products, RLD, RS |
| INDOCIN | Zyla Life Sciences | N-018332 RX | 1985-10-10 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
|---|---|---|
| indocin | New Drug Application | 2024-12-16 |
| indocin sr | ANDA | 2010-01-12 |
| indomethacin | ANDA | 2025-09-26 |
| indomethacin er | ANDA | 2010-04-16 |
| indomethacin extended-release | ANDA | 2017-12-20 |
| tivorbex | New Drug Application | 2018-01-31 |
Expiration | Code | ||
|---|---|---|---|
INDOMETHACIN, INDOMETHACIN, ZYDUS | |||
| 2024-01-30 | CGT | ||

Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | — | — | 1 | — | — | 1 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | — | — | 1 | — | — | 1 |
| Squamous cell carcinoma | D002294 | — | — | — | — | 1 | — | — | 1 |
| Drug common name | Indomethacin |
| INN | indometacin |
| Description | Indometacin is a member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It has a role as an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an analgesic, a gout suppressant, a drug metabolite, a xenobiotic metabolite, a xenobiotic, an environmental contaminant and a non-steroidal anti-inflammatory drug. It is a N-acylindole, a member of monochlorobenzenes, an aromatic ether and a member of indole-3-acetic acids. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | ![]() |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 |
| PDB | — |
| CAS-ID | 53-86-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL6 |
| ChEBI ID | 49662 |
| PubChem CID | 3715 |
| DrugBank | DB00328 |
| UNII ID | XXE1CET956 (ChemIDplus, GSRS) |










