Indobufen
Indobufen is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronary artery disease | D003324 | — | I25.1 | — | — | — | 4 | 1 | 5 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | 2 | 1 | 3 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | 2 | — | 2 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | 1 | — | 1 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | 1 | — | 1 |
| Peptic esophagitis | D004942 | EFO_1001095 | — | — | — | — | 1 | — | 1 |
| Ischemic stroke | D000083242 | — | — | — | — | — | 1 | — | 1 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | 1 | — | 1 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | 1 | — | 1 |
| Cerebral infarction | D002544 | — | I63 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | 1 | — | — | 1 |
| Thromboembolism | D013923 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronary disease | D003327 | — | — | — | — | — | — | 1 | 1 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 1 | 1 |
| Percutaneous coronary intervention | D062645 | — | — | — | — | — | — | 1 | 1 |
| Dual anti-platelet therapy | D000080903 | — | — | — | — | — | — | 1 | 1 |
| Aging | D000375 | GO_0007568 | R41.81 | — | — | — | — | 1 | 1 |
| Platelet aggregation | D010974 | GO_0070527 | — | — | — | — | — | 1 | 1 |
| Pathologic constriction | D003251 | — | — | — | — | — | — | 1 | 1 |
| Vertebrobasilar insufficiency | D014715 | EFO_1001449 | G45.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Indobufen |
| INN | indobufen |
| Description | Indobufen is a member of isoindoles. |
| Classification | Small molecule |
| Drug class | non-steriodal anti-inflammatory agents, fenbufen derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCC(C(=O)O)c1ccc(N2Cc3ccccc3C2=O)cc1 |
Identifiers
| PDB | — |
| CAS-ID | 63610-08-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1765292 |
| ChEBI ID | — |
| PubChem CID | 107641 |
| DrugBank | — |
| UNII ID | 6T9949G4LZ (ChemIDplus, GSRS) |
Target
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Variants
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Trends
PubMed Central
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Additional graphs summarizing 276 documents
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Safety
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Adverse Events
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64 adverse events reported
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