Indiplon
Indiplon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target gamma-aminobutyric acid receptor subunit alpha-1.
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Commercial
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | 2 | — | — | 2 |
| Depression | D003863 | — | F33.9 | — | — | 1 | — | — | 1 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Indiplon |
| INN | indiplon |
| Description | Indiplon is a member of pyrimidines. |
| Classification | Small molecule |
| Drug class | non-benzodiazepine anxiolytics, sedatives, hypnotics |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)N(C)c1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 |
Identifiers
| PDB | — |
| CAS-ID | 325715-02-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL262075 |
| ChEBI ID | — |
| PubChem CID | 6450813 |
| DrugBank | DB12590 |
| UNII ID | 8BT63DA42E (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
GABRA1
GABRA1
Organism
Homo sapiens
Gene name
GABRA1
Gene synonyms
NCBI Gene ID
Protein name
gamma-aminobutyric acid receptor subunit alpha-1
Protein synonyms
GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid type A receptor alpha1 subunit
Uniprot ID
Mouse ortholog
Gabra1 (14394)
gamma-aminobutyric acid receptor subunit alpha-1 (P62812)
Variants
No data
Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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