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AboutPricing
Drug ReportsIndinavir
Crixivan(indinavir)
Crixivan (indinavir) is a small molecule pharmaceutical. Indinavir was first approved as Crixivan on 1996-03-13. It is used to treat acquired immunodeficiency syndrome in the USA. It has been approved in Europe to treat HIV infections.
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YTD
1Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
urogenital diseasesD000091642
immune system diseasesD007154
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Indinavir sulfate
Tradename
Company
Number
Date
Products
CRIXIVANMerck & CoN-020685 DISCN1996-03-13
4 products, RLD
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FDA
EMA
Brand Name
Status
Last Update
crixivanNew Drug Application2012-06-14
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
acquired immunodeficiency syndromeEFO_0000765D000163B20
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J05: Antivirals for systemic use
— J05A: Direct acting antivirals
— J05AE: Protease inhibitors, direct acting antivirals
— J05AE02: Indinavir
HCPCS
No data
Clinical
Clinical Trials
112 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B201833621
InfectionsD007239EFO_0000544——1—1—2
Hemophilia aD006467EFO_0007267D66———1—1
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameIndinavir
INNindinavir
Description
Indinavir is a N-(2-hydroxyethyl)piperazine, a piperazinecarboxamide and a dicarboxylic acid diamide. It has a role as a HIV protease inhibitor.
Classification
Small molecule
Drug classantivirals: HIV protease inhibitors (saquinavir type)
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Structure (InChI/SMILES or Protein Sequence)
CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O
Identifiers
PDB—
CAS-ID150378-17-9
RxCUI—
ChEMBL IDCHEMBL115
ChEBI ID44032
PubChem CID5362440
DrugBankDB00224
UNII ID9MG78X43ZT (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
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Estimated US medical usage
Indinavir
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 8,201 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,867 adverse events reported
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