Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ZYDELIG | Gilead Sciences | N-205858 RX | 2014-07-23 | 2 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
zydelig | New Drug Application | 2025-02-20 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
non-hodgkin lymphoma | — | D008228 | C85.9 |
lymphoid leukemia | — | D007945 | C91 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 8 | 12 | 6 | — | 3 | 27 |
Leukemia | D007938 | — | C95 | 5 | 5 | 6 | — | 3 | 19 |
Lymphoid leukemia | D007945 | — | C91 | 5 | 6 | 6 | — | 3 | 19 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 6 | 5 | 2 | — | 2 | 13 |
Follicular lymphoma | D008224 | — | C82 | 4 | 4 | 1 | — | 1 | 9 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
B-cell lymphoma | D016393 | — | — | 5 | 2 | — | — | 2 | 9 |
Mantle-cell lymphoma | D020522 | — | C83.1 | 3 | 1 | — | — | — | 4 |
B-cell lymphoma marginal zone | D018442 | — | C88.4 | 2 | 3 | — | — | — | 4 |
Waldenstrom macroglobulinemia | D008258 | — | C88.0 | 1 | 3 | — | — | — | 4 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 2 | 1 | — | — | — | 3 |
Recurrence | D012008 | — | — | 2 | 1 | — | — | 1 | 3 |
Hematologic neoplasms | D019337 | — | — | 1 | 1 | — | — | — | 2 |
Non-small-cell lung carcinoma | D002289 | — | — | 1 | 1 | — | — | — | 1 |
Lung neoplasms | D008175 | — | C34.90 | 1 | 1 | — | — | — | 1 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pancreatic ductal carcinoma | D021441 | — | — | 1 | — | — | — | — | 1 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
Adenocarcinoma | D000230 | — | — | 1 | — | — | — | — | 1 |
Essential thrombocythemia | D013920 | — | D47.3 | 1 | — | — | — | — | 1 |
Polycythemia vera | D011087 | — | D45 | 1 | — | — | — | — | 1 |
Primary myelofibrosis | D055728 | — | D47.4 | 1 | — | — | — | — | 1 |
Thrombocytosis | D013922 | — | D75.83 | 1 | — | — | — | — | 1 |
Polycythemia | D011086 | EFO_0005804 | D75.1 | 1 | — | — | — | — | 1 |
Allergic rhinitis | D065631 | — | J30.9 | 1 | — | — | — | — | 1 |
Rhinitis | D012220 | EFO_0008521 | J31 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Digestive signs and symptoms | D012817 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Idelalisib |
INN | idelalisib |
Description | Idelalisib is a member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is a member of purines, an organofluorine compound, a member of quinazolines, an aromatic amine and a secondary amino compound. |
Classification | Small molecule |
Drug class | phosphatidylinositol 3-kinase (PI3K) inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 |
PDB | — |
CAS-ID | 870281-82-6 |
RxCUI | — |
ChEMBL ID | CHEMBL2216870 |
ChEBI ID | 82701 |
PubChem CID | 11625818 |
DrugBank | DB09054 |
UNII ID | YG57I8T5M0 (ChemIDplus, GSRS) |