Icodextrin
Extraneal (icodextrin) is an unknown pharmaceutical. Icodextrin was first approved as Extraneal on 2002-12-20. It is used to treat ascites and edema in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
Extraneal
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| extraneal | New Drug Application | 2025-06-30 |
Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
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HCPCS
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Clinical
Clinical Trials
414 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 1 | 2 | 2 | 4 | 9 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | 2 | 1 | — | 3 |
| Continuous ambulatory peritoneal dialysis | D010531 | — | — | — | — | 1 | 2 | — | 3 |
| Peritoneal dialysis | D010530 | — | — | — | — | — | 2 | — | 2 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | — | — | — | 1 | — | 1 |
| Hypertriglyceridemia | D015228 | EFO_0004211 | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fibrosis | D005355 | — | — | — | — | — | — | 1 | 1 |
| Tissue adhesions | D000267 | — | — | — | — | — | — | 1 | 1 |
| Cell adhesion | D002448 | — | — | — | — | — | — | 1 | 1 |
| Dialysis | D003956 | — | — | — | — | — | — | 1 | 1 |
| Recurrence | D012008 | — | — | — | — | — | — | 1 | 1 |
| Intestinal obstruction | D007415 | — | K56.60 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Icodextrin |
| INN | icodextrin |
| Description | Icodextrin (INN, USAN) is a colloid osmotic agent, derived from maltodextrin, used in form of an aqueous solution for peritoneal dialysis under the trade name Extraneal, and after gynecological laparoscopic surgery for the reduction of post-surgical adhesions (fibrous bands that form between tissues and organs) under the trade name Adept.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 9005-79-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201472 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB00702 |
| UNII ID | 2NX48Z0A9G (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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34,043 adverse events reported
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