Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ADVIL COLD AND SINUS | GSK | N-021374 OTC | 2002-05-30 | 1 products, RLD, RS |
CHILDREN'S ADVIL COLD | GSK | N-021373 OTC | 2002-04-18 | 1 products |
ADVIL COLD AND SINUS | GSK | N-019771 OTC | 1989-09-19 | 1 products, RLD, RS |
CHILDREN'S MOTRIN COLD | Johnson & Johnson | N-021128 OTC | 2000-08-01 | 1 products, RLD, RS |
SINE-AID IB | Johnson & Johnson | N-019899 OTC | 1992-12-31 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MIDOL LIQUID GELS | BionPharma | N-021472 OTC | 2002-10-18 | 1 products, RLD, RS |
CALDOLOR | Cumberland Pharmaceuticals | N-022348 RX | 2009-06-11 | 2 products, RLD, RS |
ADVIL LIQUI-GELS | GSK | N-020402 OTC | 1995-04-20 | 1 products, RLD, RS |
ADVIL MIGRAINE LIQUI-GELS | GSK | N-020402 OTC | 2000-03-16 | 1 products, RLD, RS |
INFANT'S ADVIL | GSK | N-020812 OTC | 2000-01-12 | 1 products, RLD, RS |
CHILDREN'S ADVIL | GSK | N-020589 OTC | 1996-06-27 | 1 products |
CHILDREN'S ADVIL-FLAVORED | GSK | N-020589 OTC | 1997-11-07 | 1 products |
CHILDREN'S ADVIL | GSK | N-020944 OTC | 1998-12-18 | 1 products |
JUNIOR STRENGTH ADVIL | GSK | N-020944 OTC | 1998-12-18 | 1 products |
ADVIL | GSK | N-018989 OTC | 1984-05-18 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
COMBOGESIC IV | Hikma Pharmaceuticals | N-215320 RX | 2023-10-17 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
COMBUNOX | Forest Laboratories | N-021378 DISCN | 2004-11-26 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
DUEXIS | Horizon Therapeutics Public | N-022519 DISCN | 2011-04-23 | 1 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
10 person ansi | OTC monograph final | 2010-06-07 |
24/7 life ibuprofen | ANDA | 2024-12-30 |
25 person ansi | OTC monograph final | 2010-06-07 |
365 everday value ibuprofen | ANDA | 2023-07-27 |
365 whole foods market ibuprofen | ANDA | 2024-11-26 |
50 person ansi | OTC monograph final | 2010-06-07 |
acetaminophen 250 mg and ibuprofen 125 mg | ANDA | 2025-02-06 |
acetaminophen and ibuprofen | ANDA | 2024-12-23 |
acetaminophen and ibuprofen (nsaid) | ANDA | 2024-12-23 |
acetaminophen and ibuprofen back pain | ANDA | 2024-04-04 |
Expiration | Code | ||
---|---|---|---|
ACETAMINOPHEN / IBUPROFEN SODIUM, COMBOGESIC IV, HIKMA | |||
2026-10-17 | NP | ||
IBUPROFEN, CALDOLOR, CUMBERLAND PHARMS | |||
2026-05-11 | NPP | ||
2024-11-19 | M-128 | ||
ACETAMINOPHEN / IBUPROFEN, COMBOGESIC, AFT PHARMS LTD | |||
2026-03-01 | NP |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Acetaminophen / Ibuprofen, Combogesic, Aft Pharms Ltd | |||
11197830 | 2039-02-27 | DP | U-3553 |
11534407 | 2039-02-27 | DP | U-3553 |
10532036 | 2025-09-22 | U-3553 | |
Acetaminophen / Ibuprofen Sodium, Combogesic Iv, Hikma | |||
11213498 | 2036-01-14 | DP | |
11389416 | 2035-07-17 | DP | |
11446266 | 2031-10-26 | U-3744, U-3745 | |
Ibuprofen, Caldolor, Cumberland Pharms | |||
9072661 | 2032-03-16 | U-2264 | |
9072710 | 2032-03-16 | U-2266 | |
11806400 | 2032-03-16 | U-3746 | |
9012508 | 2030-09-14 | U-981 | |
8735452 | 2029-09-30 | U-981 | |
8871810 | 2029-09-30 | U-981 | |
9114068 | 2029-09-30 | U-1735 | |
9138404 | 2029-09-30 | U-1756 | |
9295639 | 2029-09-30 | U-1756 | |
9649284 | 2029-09-30 | U-2018 | |
Chlorpheniramine Maleate / Ibuprofen / Pseudoephedrine Hydrochloride, Advil Allergy Sinus, Haleon Us Holdings | |||
7863287 | 2027-02-28 | DP | |
Famotidine / Ibuprofen, Duexis, Horizon | |||
8067451 | 2026-07-18 | DP | U-1196 |
8309127 | 2026-07-18 | DP | |
8318202 | 2026-07-18 | DP | |
8449910 | 2026-07-18 | DP | |
8501228 | 2026-07-18 | U-1196 | |
Chlorpheniramine Maleate / Ibuprofen / Pseudoephedrine Hydrochloride, Children'S Advil Allergy Sinus, Haleon Us Holdings | |||
10238640 | 2024-05-25 | DP |
Code | Description |
---|---|
J1741 | Injection, ibuprofen, 100 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Postoperative pain | D010149 | — | G89.18 | 9 | 18 | 25 | 48 | 56 | 152 |
Pain | D010146 | EFO_0003843 | R52 | 16 | 17 | 25 | 36 | 31 | 124 |
Patent ductus arteriosus | D004374 | — | Q25.0 | 2 | 15 | 13 | 9 | 19 | 54 |
Healthy volunteers/patients | — | — | — | 45 | — | — | 3 | 3 | 51 |
Acute pain | D059787 | — | R52 | 5 | 6 | 7 | 15 | 17 | 48 |
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 6 | 8 | 8 | 14 | 13 | 47 |
Back pain | D001416 | — | M54 | 3 | 3 | 4 | 16 | 18 | 43 |
Low back pain | D017116 | — | M54.5 | — | 3 | 5 | 14 | 15 | 36 |
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 4 | 5 | 3 | 8 | 13 | 31 |
Bone fractures | D050723 | EFO_0003931 | T14.8 | 2 | 1 | 3 | 11 | 9 | 26 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | 2 | — | 9 | 12 |
Neoplasms | D009369 | — | C80 | 1 | 3 | 2 | — | 4 | 10 |
Lung diseases | D008171 | EFO_0003818 | J98.4 | — | — | 1 | — | 5 | 6 |
Ulcer | D014456 | MPATH_579 | — | — | — | 2 | — | 4 | 6 |
Anesthesia and analgesia | D000760 | — | — | 2 | 3 | 1 | — | 1 | 5 |
Temporomandibular joint disorders | D013705 | — | M26.6 | 1 | 2 | 1 | — | 3 | 5 |
Temporomandibular joint dysfunction syndrome | D013706 | — | — | 1 | 2 | 1 | — | 3 | 5 |
Tendinopathy | D052256 | EFO_1001434 | M77.9 | — | — | 1 | — | 4 | 5 |
Breast diseases | D001941 | — | N60-N65 | — | — | 1 | — | 3 | 4 |
Local anesthesia | D000772 | — | — | — | 2 | 1 | — | 2 | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Stroke | D020521 | EFO_0000712 | I63.9 | 2 | 1 | — | — | 11 | 14 |
Cognitive dysfunction | D060825 | — | G31.84 | 1 | 2 | — | — | 7 | 10 |
Brain injuries | D001930 | — | S06.9 | — | 1 | — | — | 6 | 7 |
Colorectal neoplasms | D015179 | — | — | — | 2 | — | — | 4 | 6 |
Traumatic brain injuries | D000070642 | — | S06 | — | 1 | — | — | 5 | 6 |
Foot and mouth disease hand | D006232 | EFO_0007294 | B08.4 | — | 1 | — | — | 4 | 5 |
Mouth diseases | D009059 | EFO_1001047 | K13 | — | 1 | — | — | 4 | 5 |
Foot-and-mouth disease | D005536 | EFO_0007277 | B08.8 | — | 1 | — | — | 4 | 5 |
Brain concussion | D001924 | — | S06.0 | — | 1 | — | — | 3 | 4 |
Spondylosis | D055009 | — | M47 | — | 1 | — | — | 2 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Therapeutic equivalency | D013810 | — | — | 5 | — | — | — | — | 5 |
Malnutrition | D044342 | EFO_0008572 | E40-E46 | 4 | — | — | — | — | 4 |
Drug interactions | D004347 | — | — | 1 | — | — | — | 1 | 2 |
Hypotension | D007022 | EFO_0005251 | I95 | 1 | — | — | — | 1 | 2 |
Thyroid diseases | D013959 | — | E00-E07 | 1 | — | — | — | 1 | 2 |
Pharmacokinetics | D010599 | — | — | 1 | — | — | — | 1 | 2 |
Tissue adhesions | D000267 | — | — | 1 | — | — | — | 1 | 2 |
Pure autonomic failure | D054970 | — | — | 1 | — | — | — | — | 1 |
Orthostatic hypotension | D007024 | — | I95.1 | 1 | — | — | — | — | 1 |
Leukemia | D007938 | — | C95 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | — | 6 | 6 |
Motor skills disorders | D019957 | — | F82 | — | — | — | — | 6 | 6 |
Male breast neoplasms | D018567 | — | — | — | — | — | — | 4 | 4 |
Laparoscopic cholecystectomy | D017081 | — | — | — | — | — | — | 4 | 4 |
Orientation | D009949 | — | — | — | — | — | — | 4 | 4 |
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | — | — | 4 | 4 |
Cholecystitis | D002764 | — | K81 | — | — | — | — | 4 | 4 |
Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 3 | 3 |
Trismus | D014313 | — | — | — | — | — | — | 3 | 3 |
Varicose ulcer | D014647 | — | — | — | — | — | — | 3 | 3 |
Drug common name | Ibuprofen |
INN | ibuprofen |
Description | Ibuprofen is a monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, an antipyretic, a xenobiotic, an environmental contaminant, a radical scavenger, a drug allergen and a geroprotector. It is functionally related to a propionic acid. It is a conjugate acid of an ibuprofen(1-). |
Classification | Small molecule |
Drug class | anti-inflammatory/analgesic agents (ibuprofen type) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CC(C)Cc1ccc(C(C)C(=O)O)cc1 |
PDB | — |
CAS-ID | 15687-27-1 |
RxCUI | — |
ChEMBL ID | CHEMBL521 |
ChEBI ID | 5855 |
PubChem CID | 3672 |
DrugBank | DB01050 |
UNII ID | WK2XYI10QM (ChemIDplus, GSRS) |