IRATUMUMAB
Iratumumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target tumor necrosis factor receptor superfamily member 8.
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Events Timeline
5D
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YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 1 | 2 | — | — | — | 2 |
| Hodgkin disease | D006689 | — | C81 | — | 1 | — | — | — | 1 |
| Large-cell lymphoma anaplastic | D017728 | — | C84.6 | — | 1 | — | — | — | 1 |
| Primary cutaneous anaplastic large cell lymphoma | D054446 | — | C86.6 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | IRATUMUMAB |
| INN | iratumumab |
| Description | Iratumumab (human mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108612 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | AYH22O1B1U (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
TNFRSF8
TNFRSF8
Organism
Homo sapiens
Gene name
TNFRSF8
Gene synonyms
CD30, D1S166E
NCBI Gene ID
Protein name
tumor necrosis factor receptor superfamily member 8
Protein synonyms
CD30, CD30L receptor, cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30
Uniprot ID
Mouse ortholog
Tnfrsf8 (21941)
tumor necrosis factor receptor superfamily member 8 (Q60846)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 23 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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