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Drug ReportsIMARADENANT
IMARADENANT
Imaradenant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target adenosine receptor A2b, adenosine receptor A1, and adenosine receptor A2a.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
7 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289212
Prostatic neoplasmsD011471C6111
Castration-resistant prostatic neoplasmsD06412911
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients22
Colorectal neoplasmsD01517911
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameIMARADENANT
INNimaradenant
Description
Imaradenant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target adenosine receptor A2b, adenosine receptor A1, and adenosine receptor A2a.
Classification
Small molecule
Drug classadenosine receptor antagonists
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Structure (InChI/SMILES or Protein Sequence)
Cc1cc(-c2nnc(N)nc2-c2ccc(F)cc2)cc(Cl)n1
Identifiers
PDB
CAS-ID1321514-06-0
RxCUI
ChEMBL IDCHEMBL4594442
ChEBI ID
PubChem CID
DrugBank
UNII ID770140J08A (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ADORA2B
ADORA2B
ADORA1
ADORA1
ADORA2A
ADORA2A
Organism
Homo sapiens
Gene name
ADORA2B
Gene synonyms
NCBI Gene ID
Protein name
adenosine receptor A2b
Protein synonyms
Uniprot ID
Mouse ortholog
Adora2b (11541)
adenosine receptor A2b (Q8BXI2)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 189 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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