Hypromellose
Hypromellose is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
FDA approval date
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Study first post date
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| eye diseases | D005128 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| advanced eye relief/ redness maximum relief | C200263 | 2024-09-25 |
| alcon tears lubricant eye drops | C200263 | 2023-12-14 |
| artificial tears | OTC monograph final | 2019-10-28 |
| artificial tears lubricant eye drops | C200263 | 2026-03-25 |
| aurovisc | C200263 | 2026-01-08 |
| aurovisc lubricant hypromellose 2208 (15000 mpa.s) gel/drops | C200263 | 2026-01-27 |
| aurovisc lubricant hypromellose 2208 (15000 mpa.s) solution/drops | OTC monograph final | 2023-01-11 |
| aurovisc oe | C200263 | 2026-01-27 |
| biomedic artificial tears | Export only | 2025-12-31 |
| bion tears | C200263 | 2023-12-14 |
Show 51 more
Indications
FDA
EMA
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Agency Specific
FDA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
590 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dry eye syndromes | D015352 | — | H04.12 | 12 | 23 | 15 | 49 | 89 | 182 |
| Keratoconjunctivitis sicca | D007638 | EFO_1000906 | — | 8 | 16 | 10 | 21 | 45 | 96 |
| Eye diseases | D005128 | EFO_0003966 | H44 | 4 | 8 | 7 | 11 | 22 | 50 |
| Glaucoma | D005901 | EFO_0000516 | H40 | 1 | 5 | 5 | 10 | 9 | 28 |
| Healthy volunteers/patients | — | — | — | 11 | 1 | 1 | 1 | 10 | 23 |
| Meibomian gland dysfunction | D000080343 | — | H02.88 | 2 | 2 | — | 6 | 11 | 19 |
| Conjunctivitis | D003231 | — | H10 | — | 1 | 3 | 9 | 4 | 16 |
| Cataract | D002386 | EFO_0001059 | H26.9 | 1 | — | — | 4 | 8 | 13 |
| Ocular hypertension | D009798 | EFO_1001069 | H40.0 | — | 3 | 2 | 8 | — | 12 |
| Open-angle glaucoma | D005902 | EFO_0004190 | H40.1 | 1 | 4 | 4 | 3 | 2 | 12 |
Show 65 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type c niemann-pick disease | D052556 | Orphanet_646 | E75.242 | 6 | 7 | 5 | — | — | 12 |
| Niemann-pick diseases | D009542 | — | E75.24 | 5 | 6 | 5 | — | — | 11 |
| Type a niemann-pick disease | D052536 | EFO_1001380 | E75.240 | 5 | 6 | 5 | — | — | 11 |
| Pick disease of the brain | D020774 | EFO_0003096 | G31.01 | 5 | 6 | 4 | — | — | 10 |
| Covid-19 | D000086382 | — | U07.1 | 2 | 5 | 1 | — | 1 | 7 |
| Cognitive dysfunction | D060825 | — | G31.84 | 1 | 1 | 3 | — | 3 | 7 |
| Corneal ulcer | D003320 | — | H16.0 | — | 2 | 3 | — | 3 | 6 |
| Frontotemporal dementia | D057180 | — | G31.0 | 5 | 2 | 1 | — | — | 6 |
| Primary progressive aphasia | D018888 | EFO_0009053 | G31.01 | 5 | 2 | 1 | — | — | 6 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 3 | — | 2 | — | — | 5 |
Show 56 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fuchs' endothelial dystrophy | D005642 | EFO_0003946 | H18.51 | — | 3 | — | — | 2 | 5 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 2 | — | — | 3 | 5 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 2 | — | — | — | 3 |
| Myelodysplastic syndromes | D009190 | — | D46 | — | 3 | — | — | — | 3 |
| Myeloid leukemia acute | D015470 | — | C92.0 | — | 3 | — | — | — | 3 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | — | 3 | — | — | — | 3 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | — | 3 | — | — | — | 3 |
| Myeloid leukemia | D007951 | — | C92 | — | 3 | — | — | — | 3 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | 1 | — | — | 2 | 3 |
| Neuralgia | D009437 | EFO_0009430 | — | 1 | 2 | — | — | 1 | 3 |
Show 95 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pharmacokinetics | D010599 | — | — | 3 | — | — | — | — | 3 |
| Hiv | D006678 | — | O98.7 | 2 | — | — | — | — | 2 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 1 | — | — | — | — | 1 |
| Lipodystrophy | D008060 | — | E88.1 | 1 | — | — | — | — | 1 |
| Hiv-associated lipodystrophy syndrome | D039682 | EFO_1001348 | — | 1 | — | — | — | — | 1 |
| Medication adherence | D055118 | EFO_0006344 | — | 1 | — | — | — | — | 1 |
| Aspergillosis | D001228 | EFO_0007157 | B44 | 1 | — | — | — | — | 1 |
| Allergic bronchopulmonary aspergillosis | D001229 | EFO_0007140 | B44.81 | 1 | — | — | — | — | 1 |
| Pulmonary aspergillosis | D055732 | EFO_1001834 | — | 1 | — | — | — | — | 1 |
| Hepacivirus | D016174 | — | — | 1 | — | — | — | — | 1 |
Show 23 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Muscle strength | D053580 | — | — | — | — | — | — | 4 | 4 |
| Body composition | D001823 | — | — | — | — | — | — | 4 | 4 |
| Resistance training | D055070 | — | — | — | — | — | — | 3 | 3 |
| Infertility | D007246 | EFO_0000545 | — | — | — | — | — | 2 | 2 |
| Psychotic disorders | D011618 | — | F20.81 | — | — | — | — | 2 | 2 |
| Corneal injuries | D065306 | — | — | — | — | — | — | 2 | 2 |
| Alopecia | D000505 | — | L64 | — | — | — | — | 2 | 2 |
| Hyperglycemia | D006943 | — | R73.9 | — | — | — | — | 2 | 2 |
| Aging | D000375 | GO_0007568 | R41.81 | — | — | — | — | 2 | 2 |
| Probiotics | D019936 | — | — | — | — | — | — | 2 | 2 |
Show 71 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Hypromellose |
| INN | hypromellose |
| Description | Hypromellose (INN), short for hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, viscoelastic polymer used in eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108956 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 0HO1H52958 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,945 adverse events reported
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