
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| XROMI | Nova Laboratories | N-216593 RX | 2024-04-04 | 1 products, RLD, RS |
| HYDREA | Waylis Therapeutics | N-016295 RX | 1982-01-01 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
|---|---|---|
| droxia | New Drug Application | 2025-09-12 |
| hydrea | New Drug Application | 2025-09-15 |
| hydroxyurea | ANDA | 2025-09-11 |
| siklos | New Drug Application | 2025-02-05 |
| xromi | New Drug Application | 2025-08-20 |
Expiration | Code | ||
|---|---|---|---|
HYDROXYUREA, SIKLOS, ADDMEDICA SAS | |||
| 2024-12-21 | ODE-177 | ||
Code | Description |
|---|---|
| S0176 | Hydroxyurea, oral, 500 mg |

Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | 1 | — | — | 1 | 2 |
| Beta-thalassemia | D017086 | Orphanet_848 | D56.1 | 1 | 1 | — | — | — | 1 |
| Thalassemia | D013789 | EFO_1001996 | D56 | 1 | 1 | — | — | — | 1 |
| Hemoglobin sc disease | D006450 | EFO_1001797 | D57.2 | 1 | 1 | — | — | — | 1 |
| Drug common name | Hydroxyurea |
| INN | hydroxycarbamide |
| Description | Hydroxyurea is a member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. It has a role as a DNA synthesis inhibitor, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an antineoplastic agent, a genotoxin, an antimetabolite, a teratogenic agent, a radical scavenger, an immunomodulator and an antimitotic. It is a member of ureas and a one-carbon compound. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | ![]() |
| Structure (InChI/SMILES or Protein Sequence) | NC(=O)NO |
| PDB | — |
| CAS-ID | 127-07-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL467 |
| ChEBI ID | 44423 |
| PubChem CID | 3657 |
| DrugBank | DB01005 |
| UNII ID | X6Q56QN5QC (ChemIDplus, GSRS) |






