Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CORTENEMA | ANI Pharmaceuticals | N-016199 RX | 1982-01-01 | 1 products, RLD, RS |
ALKINDI SPRINKLE | Eton Pharmaceuticals | N-213876 RX | 2020-09-29 | 4 products, RLD, RS |
KHINDIVI | Eton Pharmaceuticals | N-218980 RX | 2025-05-28 | 1 products, RLD, RS |
CORTEF | Pharmacia & Upjohn | N-008697 RX | 1982-01-01 | 3 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CORTISPORIN | Monarch Pharmaceuticals | N-050218 DISCN | 1985-08-09 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
WESTCORT | Sun Pharmaceutical Industries | N-017950 DISCN | 1982-01-01 | 1 products, RLD |
WESTCORT | Sun Pharmaceutical Industries | N-018726 DISCN | 1983-08-08 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
XERESE | Bausch Health Companies | N-022436 RX | 2009-07-31 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CHLOROMYCETIN HYDROCORTISONE | Parkedale Pharmaceuticals | N-050202 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
HYDROCORTONE | Merck & Co | N-012052 DISCN | 1982-01-01 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
SOLU-CORTEF | Pharmacia & Upjohn | N-009866 RX | 1982-01-01 | 4 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ACHROMYCIN | Lederle Laboratories | N-050272 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CORTISPORIN | Casper Pharma | N-050416 DISCN | 1982-01-01 | 1 products, RLD |
CORTISPORIN | Monarch Pharmaceuticals | N-050168 DISCN | 1984-05-04 | 1 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
OPHTHOCORT | Parkedale Pharmaceuticals | N-050201 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CASPORYN HC | Casper Pharma | N-060613 RX | 1982-01-01 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
VOSOL HC | Saptalis Pharmaceuticals | N-012770 RX | 1982-01-01 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CORTEF | Pharmacia & Upjohn | N-009900 DISCN | 1982-01-01 | 1 products |
Brand Name | Status | Last Update |
---|---|---|
OTC monograph not final | 2012-08-24 | |
141016 hydrocortisone 0.5% / hydroquinone 4% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
141017 hydrocortisone 0.5% / hydroquinone 6% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
141060 hydrocortisone 0.5% / hydroquinone 4% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
141061 hydrocortisone 0.5% / hydroquinone 8% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
999 itch relieving | OTC monograph not final | 2016-11-14 |
advanced anti-itch therapy | OTC monograph not final | 2016-06-14 |
afassco 1% hydrocortisone | OTC monograph not final | 2023-01-12 |
aftate hydrocortisone cream | OTC monograph not final | 2016-03-31 |
ala-scalp | ANDA | 2025-01-08 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Lymphoma | D008223 | — | C85.9 | 67 | 160 | 68 | 8 | 17 | 279 |
Leukemia | D007938 | — | C95 | 60 | 131 | 48 | 10 | 15 | 229 |
Syndrome | D013577 | — | — | 24 | 67 | 35 | 21 | 60 | 193 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 37 | 84 | 42 | 12 | 8 | 158 |
Lymphoid leukemia | D007945 | — | C91 | 34 | 78 | 36 | 9 | 7 | 143 |
Prostatic neoplasms | D011471 | — | C61 | 17 | 70 | 39 | 6 | 13 | 135 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 24 | 56 | 15 | 2 | 1 | 81 |
B-cell lymphoma | D016393 | — | — | 27 | 53 | 14 | 2 | 2 | 81 |
Covid-19 | D000086382 | — | U07.1 | 2 | 10 | 30 | 7 | 33 | 78 |
Arthritis | D001168 | EFO_0005856 | M05-M14 | 3 | 20 | 22 | 22 | 12 | 77 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-hodgkin lymphoma | D008228 | — | C85.9 | 29 | 57 | 21 | — | 5 | 93 |
Graft vs host disease | D006086 | — | D89.81 | 15 | 37 | 16 | — | 7 | 67 |
Myelodysplastic syndromes | D009190 | — | D46 | 17 | 44 | 5 | — | 4 | 62 |
Preleukemia | D011289 | — | — | 16 | 35 | 5 | — | 4 | 53 |
Myeloid leukemia acute | D015470 | — | C92.0 | 21 | 22 | 5 | — | — | 40 |
Myeloid leukemia | D007951 | — | C92 | 17 | 21 | 4 | — | — | 35 |
Carcinoma | D002277 | — | C80.0 | 5 | 19 | 3 | — | 7 | 30 |
Premature birth | D047928 | EFO_0003917 | O60 | 3 | 1 | 1 | — | 21 | 26 |
Hematologic neoplasms | D019337 | — | — | 8 | 16 | 1 | — | 3 | 23 |
Myeloproliferative disorders | D009196 | — | D47.1 | 5 | 17 | 1 | — | 2 | 23 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Adenocarcinoma | D000230 | — | — | 1 | 16 | — | — | — | 16 |
T-cell lymphoma | D016399 | — | — | 7 | 13 | — | — | — | 16 |
T-cell lymphoma peripheral | D016411 | — | — | 6 | 11 | — | — | — | 13 |
Opioid-related disorders | D009293 | EFO_0005611 | F11 | 2 | 5 | — | — | 5 | 11 |
Overweight | D050177 | — | E66.3 | 3 | 1 | — | — | 8 | 11 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | — | 1 | — | — | 9 | 10 |
Head and neck neoplasms | D006258 | — | — | 2 | 4 | — | — | 5 | 9 |
Anorexia | D000855 | — | R63.0 | — | 1 | — | — | 8 | 9 |
Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | — | 1 | — | — | 8 | 9 |
Melanoma | D008545 | — | — | 4 | 6 | — | — | — | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Alcohol drinking | D000428 | EFO_0004329 | — | 3 | — | — | — | 10 | 13 |
Blood pressure | D001794 | EFO_0004325 | — | 2 | — | — | — | 5 | 7 |
Cardiac arrhythmias | D001145 | EFO_0004269 | I49.9 | 1 | — | — | — | 4 | 5 |
Pathologic dilatation | D004108 | — | — | 1 | — | — | — | 4 | 5 |
Fibromyalgia | D005356 | EFO_0005687 | M79.1 | 1 | — | — | — | 4 | 5 |
Malnutrition | D044342 | EFO_0008572 | E40-E46 | 1 | — | — | — | 3 | 4 |
Myofascial pain syndromes | D009209 | EFO_1001054 | — | 1 | — | — | — | 3 | 4 |
Problem behavior | D000066553 | — | — | 1 | — | — | — | 3 | 4 |
Sleep deprivation | D012892 | — | F51.12 | 2 | — | — | — | 1 | 3 |
Adrenal gland diseases | D000307 | — | E27.9 | 1 | — | — | — | 2 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Dental anxiety | D016854 | — | — | — | — | — | — | 9 | 9 |
Dental implants | D015921 | — | — | — | — | — | — | 9 | 9 |
Psychological distress | D000079225 | — | — | — | — | — | — | 8 | 8 |
Psychological burnout | D000077062 | — | Z73.0 | — | — | — | — | 6 | 6 |
Wound healing | D014945 | GO_0042060 | — | — | — | — | — | 6 | 6 |
Nursing care | D009732 | — | — | — | — | — | — | 6 | 6 |
Occupational stress | D000073397 | — | — | — | — | — | — | 6 | 6 |
Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 6 | 6 |
Rotator cuff injuries | D000070636 | — | M75.1 | — | — | — | — | 5 | 5 |
Professional burnout | D002055 | — | — | — | — | — | — | 5 | 5 |
Drug common name | Hydrocortisone |
INN | hydrocortisone |
Description | Cortisol is a 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. It has a role as an anti-inflammatory drug, an anti-allergic agent, an anti-asthmatic drug, a human metabolite, a mouse metabolite and a drug allergen. It is a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(4) steroid, a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy-C21-steroid and a glucocorticoid. It derives from a hydride of a pregnane. |
Classification | Small molecule |
Drug class | cortisone derivatives |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO |
PDB | — |
CAS-ID | 50-23-7 |
RxCUI | — |
ChEMBL ID | CHEMBL389621 |
ChEBI ID | 17650 |
PubChem CID | 5754 |
DrugBank | DB00741 |
UNII ID | WI4X0X7BPJ (ChemIDplus, GSRS) |