PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsHibiclens
Chlorhexidine gluconate
Avagard, Bioscrub, Chg, Chloraprep, Chloraprep One-step, Chloraprep Swabstick, Chlorhexidine, Cida-stat, Exidine, Hibiclens, Hibistat, Peridex, Periogard, Prevantics, Prevantics Swabstick, Soluprep (chlorhexidine gluconate) is a small molecule pharmaceutical. Chlorhexidine gluconate was first approved as Hibiclens on 1982-01-01. It is used to treat gram-negative bacterial infections, gram-positive bacterial infections, infectious skin diseases, oral candidiasis, and periodontal diseases in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
stomatognathic diseasesD009057
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
(qiqing) chlorhexidine gluconate alcohol disinfectantOTC monograph not final2020-05-15
3m avagardNew Drug Application2024-08-01
3m avagard dC2002632024-08-01
3m avagard foaming instant hand antisepticC2002632024-08-01
3m avagard foaming instant hand antisepticOTC monograph not final2011-05-19
3m soluprep sNew Drug Application2024-08-01
acclean chlorhexidine gluconate 0.12% oral rinseANDA2023-02-28
alcohol disinfectant wipesOTC monograph not final2020-06-24
anti mucedine feminine washunapproved drug other2021-04-20
anti-bacterial gelC2002632024-05-16
Show 129 more
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration
Code
CHLORHEXIDINE GLUCONATE / ISOPROPYL ALCOHOL, SOLUPREP S, 3M HEALTH CARE
2026-01-20M-292
Patent Expiration
Patent
Expires
Flag
FDA Information
Chlorhexidine Gluconate, Chlorhexidine Gluconate, Sage Prods
79350932027-10-02DPU-1022
74275742026-04-25DP
77178892025-02-27DPU-1022
70669162024-02-17U-737
Chlorhexidine Gluconate / Isopropyl Alcohol, Chloraprep One-Step, Becton Dickinson Co
74223882027-04-25DPU-1397
69913942024-01-31DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AB: Antiinfectives and antiseptics for local oral treatment
— A01AB03: Chlorhexidine
B: Blood and blood forming organ drugs
— B05: Blood substitutes and perfusion solutions
— B05C: Irrigating solutions, blood substitutes and perfusion
— B05CA: Antiinfective irrigating solutions
— B05CA02: Chlorhexidine
D: Dermatologicals
— D08: Antiseptics and disinfectants
— D08A: Antiseptics and disinfectants
— D08AC: Biguanides and amidines as antiseptics and disinfectants
— D08AC02: Chlorhexidine
— D08AC52: Chlorhexidine, combinations
— D09: Medicated dressings
— D09A: Medicated dressings
— D09AA: Medicated dressings with antiinfectives
— D09AA12: Chlorhexidine
R: Respiratory system drugs
— R02: Throat preparations
— R02A: Throat preparations
— R02AA: Antiseptic throat preparations
— R02AA05: Chlorhexidine
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AX: Other antiinfectives in atc
— S01AX09: Chlorhexidine
— S02: Otologicals
— S02A: Antiinfective drugs, otologic
— S02AA: Antiinfectives
— S02AA09: Chlorhexidine
— S03: Ophthalmological and otological preparations
— S03A: Antiinfectives, ophthalmologic and otologic
— S03AA: Antiinfectives
— S03AA04: Chlorhexidine
HCPCS
No data
Clinical
Clinical Trials
1063 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CatheterizationD002404———111—2
InfectionsD007239EFO_0000544————112
Communicable diseasesD003141—————112
Hand hygieneD063373—————1—1
Skin diseasesD012871—L00-L99———1—1
Healthy volunteers/patients——————1—1
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Dental cariesD003731EFO_0003819K02————22
Ventilator-associated pneumoniaD053717EFO_1001865J95.851————11
PneumoniaD011014EFO_0003106—————11
SepsisD018805HP_0100806A41.9————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameChlorhexidine gluconate
INNchlorhexidine
Description
Chlorhexidine is a bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. It has a role as an antiinfective agent and an antibacterial agent. It is a member of biguanides and a member of monochlorobenzenes. It is functionally related to a biguanide.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
N=C(NCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1)NC(=N)Nc1ccc(Cl)cc1.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Identifiers
PDB—
CAS-ID18472-51-0
RxCUI—
ChEMBL IDCHEMBL4297088
ChEBI ID—
PubChem CID9552079
DrugBankDB00878
UNII IDR4KO0DY52L (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 36,278 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
9,180 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use