Hexachlorophene
Pre-op (hexachlorophene) is a small molecule pharmaceutical. Hexachlorophene was first approved as Scrubteam surgical spongebrush on 1982-01-01. It is used to treat acne vulgaris and communicable diseases in the USA. It is known to target N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Pre-op (discontinued: Dial, E-z scrub, Gamophen, Germa-medica mg, Hexa-germ, Hexascrub, Phiso-scrub, Phisohex, Scrubteam surgical spongebrush, Septi-soft, Septisol, Soy-dome, Turgex)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Hexachlorophene
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PRE-OP | Davis & Geck | N-017433 RX | 1982-01-01 | 1 products, RLD, RS |
| PRE-OP II | Davis & Geck | N-017433 RX | 1982-01-01 | 1 products, RLD |
Show 17 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| bd e-z scrub | C200263 | 2024-12-13 |
| bd e-z scrub 107 | ANDA | 2024-12-12 |
| bd e-z scrub clorhexidine gluconate antiseptic | New Drug Application | 2012-01-11 |
| benzethonium chloride solution | OTC monograph not final | 2015-12-01 |
| dial | OTC monograph not final | 2014-02-24 |
| dial acne | OTC monograph final | 2014-06-06 |
| dial acne control deep cleansing body wash | OTC monograph final | 2014-07-01 |
| dial acne control deep cleansing face wash | OTC monograph final | 2014-07-01 |
| dial advanced clean | C200263 | 2024-11-11 |
| dial aloe | OTC monograph not final | 2014-05-27 |
Show 53 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| acne vulgaris | EFO_0003894 | D000152 | L70 |
| communicable diseases | — | D003141 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
984 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | — | — | 2 | — | 2 |
| Communicable diseases | D003141 | — | — | — | — | — | 1 | — | 1 |
| Surgical wound infection | D013530 | — | — | — | — | — | 1 | — | 1 |
| Respiratory tract diseases | D012140 | — | — | — | — | — | 1 | — | 1 |
| Respiration disorders | D012120 | — | J00-J99 | — | — | — | 1 | — | 1 |
| Staphylococcal infections | D013203 | — | A49.01 | — | — | — | 1 | — | 1 |
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | 1 | 1 | — | — | — | 1 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Hexachlorophene |
| INN | hexachlorophene |
| Description | Hexachlorophene is an organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union. It has a role as an antiseptic drug, an acaricide, an antibacterial agent and an antifungal agrochemical. It is a polyphenol, a trichlorobenzene and a bridged diphenyl fungicide. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl |
Identifiers
| PDB | — |
| CAS-ID | 70-30-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL496 |
| ChEBI ID | 5693 |
| PubChem CID | 3598 |
| DrugBank | DB00756 |
| UNII ID | IWW5FV6NK2 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
NAPEPLD
NAPEPLD
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Hexachlorophene
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 40,991 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
71,249 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use