PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsGlimepiride
Amaryl, Avaglim(glimepiride)
Avaglim, Avandaryl, Duetact, Glimepiride, Tandemact (glimepiride) is a small molecule pharmaceutical. Glimepiride was first approved as Amaryl on 1995-11-30. It is used to treat type 2 diabetes mellitus in the USA. It has been approved in Europe to treat type 2 diabetes mellitus.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nutritional and metabolic diseasesD009750
endocrine system diseasesD004700
Trade Name
FDA
EMA
Glimepiride (discontinued: Amaryl, Glimepiride)
Combinations
Duetact, Pioglitazone glimepiride (discontinued: Avandaryl, Rosiglitazone glimepiride)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Glimepiride
Tradename
Company
Number
Date
Products
AMARYLSanofiN-020496 DISCN1995-11-30
3 products, RLD
Hide discontinued
Glimepiride
+
Pioglitazone hydrochloride
Tradename
Company
Number
Date
Products
DUETACTTakedaN-021925 RX2006-07-28
2 products, RLD
Glimepiride
+
Rosiglitazone maleate
Tradename
Company
Number
Date
Products
AVANDARYLSB PharmcoN-021700 DISCN2005-11-23
5 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
duetactNew Drug Application2025-03-27
glimepirideANDA2025-03-25
glimepiride 3 mgANDA2024-08-20
pioglitazone and glimepirideNDA authorized generic2021-12-16
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
type 2 diabetes mellitusEFO_0001360D003924E11
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Glimepiride / Pioglitazone Hydrochloride, Duetact, Takeda Pharms Usa
80711302028-06-08DP
77001282027-01-30DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A10: Drugs used in diabetes
— A10B: Blood glucose lowering drugs, excl. insulins
— A10BB: Sulfonylureas for blood glucose lowering
— A10BB12: Glimepiride
— A10BD: Combinations of oral blood glucose lowering drugs
— A10BD04: Glimepiride and rosiglitazone
— A10BD06: Glimepiride and pioglitazone
HCPCS
No data
Clinical
Clinical Trials
270 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———————22
MalnutritionD044342EFO_0008572E40-E46————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameGlimepiride
INNglimepiride
Description
Glimepiride is a sulfonamide, a N-acylurea and a N-sulfonylurea. It has a role as a hypoglycemic agent and an insulin secretagogue.
Classification
Small molecule
Drug classantidiabetics
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCC1=C(C)CN(C(=O)NCCc2ccc(S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)cc2)C1=O
Identifiers
PDB—
CAS-ID93479-97-1
RxCUI—
ChEMBL IDCHEMBL1481
ChEBI ID5383
PubChem CID3476
DrugBankDB00222
UNII ID6KY687524K (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Glimepiride
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Glimepiride
+
Pioglitazone
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Glimepiride
+
Rosiglitazone
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 8,379 documents
View more details
Safety
Black-box Warning
Black-box warning for: Duetact, Pioglitazone and glimepiride
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
10,391 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use